Evidence map›Paper›PMID 41164270›Full record

ArticleFood science & nutrition2025

Association Between Dietary Vitamin K Intake With Cancer Cachexia and Mortality: NHANES 1999-2018.

Guoming Chen, Siran Lai, Geer Lin, Tianyi Li, Xiangjun Qi, Cheng Zhang, Guang Chen, Guoyi Tang, Ning Wang, Yibin Feng

Abstract read
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Guoming ChenSchool of Chinese Medicine, Li Ka Shing Faculty of Medicine The University of Hong Kong Hong Kong SAR China.
Siran LaiThe First Clinical Medical School of Guangzhou University of Chinese Medicine Guangzhou China.
Geer LinFoshan Clinical Medical College, Guangzhou University of Chinese Medicine Guangzhou China.
Tianyi LiSchool of Public Health and Management, Guangzhou University of Chinese Medicine Guangzhou China.
Xiangjun QiThe First Clinical Medical School of Guangzhou University of Chinese Medicine Guangzhou China.
Cheng ZhangSchool of Chinese Medicine, Li Ka Shing Faculty of Medicine The University of Hong Kong Hong Kong SAR China.
Guang ChenSchool of Chinese Medicine, Li Ka Shing Faculty of Medicine The University of Hong Kong Hong Kong SAR China.
Guoyi TangSchool of Chinese Medicine, Li Ka Shing Faculty of Medicine The University of Hong Kong Hong Kong SAR China.
Ning WangSchool of Chinese Medicine, Li Ka Shing Faculty of Medicine The University of Hong Kong Hong Kong SAR China.
Yibin FengSchool of Chinese Medicine, Li Ka Shing Faculty of Medicine The University of Hong Kong Hong Kong SAR China.ORCID https://orcid.org/0000-0002-0241-670X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research on the association between the development of cancer cachexia and dietary nutrient intake remains insufficient. We discussed the screening of dietary intake risks for cancer cachexia and further investigated the impact of vitamin K on the prognosis of cancer cachexia survivors. We ultimately analyzed 3489 NHANES participants across 10 cycles. Multivariate logistic regression analysis and restricted cubic spline (RCS) methods were used to explore the relationship between the intake of most dietary nutrients and the incidence of cancer cachexia. Further, multivariate Cox regression analysis, Kaplan-Meier survival analysis, and RCS analysis were employed to examine the association between vitamin K intake and mortality among cancer cachexia survivors. The multivariate logistic regression model revealed that vitamin K, dietary fiber, β-carotene, food folate, and magnesium might increase the risk of cancer cachexia. In contrast, energy, α-carotene, retinol, lycopene, iron, and copper might reduce the risk of cancer cachexia. Further RCS analysis showed an inverse U-shaped relationship between vitamin K intake and the incidence of cancer cachexia. Multivariate Cox regression analysis indicated that the high vitamin K intake group could reduce the risk of all-cause mortality (HR = 0.71; 95% CI, 0.60-0.84;

Indexed as

cancer cachexiadietary risk factorsmortalityNHANESvitamin K

Identifiers

PMID41164270
PMCPMC12566881

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.