Evidence map›Paper›PMID 41164230›Full record

ArticleFrontiers in veterinary science2025

Genomic characterisation of endangered Landim pigs reveals distinctive features and immune-related selection.

Fábio Teixeira, Pedro Sá, Dulce Santos, Carmen Garrine, Rosa Zimba, Laurinda Augusto, Endika Varela-Martínez, Hermenegildo Chiaia, Kiala Sebastino, José M Cordeiro and 3 more

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fábio TeixeiraUniversidade de Évora, MED (Mediterranean Institute for Agriculture, Environment and Development) & CHANGE (Global Change and Sustainability Institute), Évora, Portugal.
Pedro SáAnimal Breeding and Genomics, Wageningen University and Research, Wageningen, Netherlands.
Dulce SantosBE, Bioinsight & Ecoa, Odivelas, Portugal.
Carmen GarrineFaculty of Veterinary, Eduardo Mondlane University, Maputo, Mozambique.
Rosa ZimbaEscola Superior de Desenvolvimento Rural de Vilankulo, University Eduardo Mondlane, Inhambane, Mozambique.
Laurinda AugustoFaculty of Veterinary, Eduardo Mondlane University, Maputo, Mozambique.
Endika Varela-MartínezDepartment of Genetics, Physical Anthropology and Animal Physiology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Leioa, Spain.
Hermenegildo ChiaiaFaculty of Veterinary Medicine, University José Eduardo dos Santos, Huambo, Angola.
Kiala SebastinoCIISA - Centre for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal.
José M CordeiroFaculty of Veterinary Medicine, University José Eduardo dos Santos, Huambo, Angola.
Alexandre LeitãoCIISA - Centre for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal.
Luís T GamaCIISA - Centre for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal.
Andreia J AmaralUniversidade de Évora, MED (Mediterranean Institute for Agriculture, Environment and Development) & CHANGE (Global Change and Sustainability Institute), Évora, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The Landim pigs of Mozambique are an important local breed, reared by smallscale farmers in extensive systems, predominantly sustained on leftover food. These pigs serve as a cornerstone of the economic stability of these communities. However, their existence is currently threatened by uncontrolled crossbreeding with commercial pig breeds. Preserving these local pigs is also crucial, given their role as a source of genetic diversity. Methods: Whole-genome resequencing of samples derived from six Landim pigs,was conducted, to characterise their genetic makeup and establishing their relationship with pig breeds worldwide. Results: Our findings suggest that Landim pigs are more closely related to Angolan pigs, although recent introgression from European cosmopolitan breeds has occurred. Discussion: Results show that Landim pigs display a unique genetic signature, with positive selection detected in variants of genes acting within the neuroimmune axis, which is fundamental for survival and immune response.

Indexed as

innate immunityLandimpigsselectionwhole-genome sequencing

Identifiers

PMID41164230
PMCPMC12560241

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.