Evidence map›Paper›PMID 41164189›Full record

ArticleFrontiers in immunology2025

Non-additive strong gene interactions cause striking differences in organ pathology and cytokine response in Leishmaniasis.

Yahya Sohrabi, Tatyana Kobets, Valeriya Volkova, Eliška Javorková, Imtissal Krayem, Alena Zajícová, Helena Havelková, Milena Svobodová, Vladimír Holáň, Peter Demant and 1 more

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Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yahya SohrabiDepartment of Medical Genetics, Third Faculty of Medicine, Charles University, Prague, Czechia.
Tatyana KobetsLaboratory of Molecular and Cellular Immunology, Institute of Molecular Genetics, Czech Academy of Sciences, Prague, Czechia.
Valeriya VolkovaLaboratory of Molecular and Cellular Immunology, Institute of Molecular Genetics, Czech Academy of Sciences, Prague, Czechia.
Eliška JavorkováDepartment of Toxicology and Molecular Epidemiology, Institute of Experimental Medicine of the Czech Academy of Sciences, Prague, Czechia.
Imtissal KrayemLaboratory of Molecular and Cellular Immunology, Institute of Molecular Genetics, Czech Academy of Sciences, Prague, Czechia.
Alena ZajícováDepartment of Toxicology and Molecular Epidemiology, Institute of Experimental Medicine of the Czech Academy of Sciences, Prague, Czechia.
Helena HavelkováLaboratory of Molecular and Cellular Immunology, Institute of Molecular Genetics, Czech Academy of Sciences, Prague, Czechia.
Milena SvobodováDepartment of Parasitology, Faculty of Science, Charles University, Prague, Czechia.
Vladimír HoláňDepartment of Toxicology and Molecular Epidemiology, Institute of Experimental Medicine of the Czech Academy of Sciences, Prague, Czechia.
Peter DemantDepartment of Molecular and Cellular Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Marie LipoldováDepartment of Medical Genetics, Third Faculty of Medicine, Charles University, Prague, Czechia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mouse strain O20 is highly resistant to parasite

Indexed as

CytokinesLeishmania majorLeishmaniasisLeishmaniasis, CutaneousAnimalsAntigens, ProtozoanFemaleMacrophagesMiceMice, Inbred C57BLSpleenAntigens, ProtozoanCytokinesasymptomatic leishmaniasisCD11b + Gr1 + cellshost-pathogen interactionleishmaniasismouse modelnovel genetic mechanisms of disease susceptibility and resistance

Identifiers

PMID41164189
PMCPMC12558852

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.