Evidence map›Paper›PMID 41164065›Full record

ReviewCureus2025

Anaesthesia for Paramyotonia Congenita: A Narrative Review.

Marianne Chee, Suhitharan Thangavelautham, Jing Hui Chen, Harikrishnan Kothandan

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marianne CheeAnaesthesiology and Critical Care, Singapore General Hospital, Singapore, SGP.
Suhitharan ThangavelauthamAnaesthesiology and Perioperative Medicine, Singapore General Hospital, Singapore, SGP.
Jing Hui ChenAnaesthesiology and Perioperative Medicine, Singapore General Hospital, Singapore, SGP.
Harikrishnan KothandanAnaesthesiology and Perioperative Medicine, Singapore General Hospital, Singapore, SGP.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paramyotonia congenita (PMC) is a rare, non-progressive neuromuscular disorder characterised by muscle stiffness and delayed relaxation following voluntary contraction or mechanical stimulation. Its rarity means many anaesthetists may encounter it only once, if ever, in their careers. This narrative review synthesises existing literature on anaesthetic management in these patients. We aim to provide anaesthetists with a clearer understanding of PMC, with particular focus on perioperative considerations, choice of anaesthetic agents, and reported outcomes. While anaesthetic techniques vary, several recurring management principles emerge, including avoidance of triggers for muscle stiffness, careful temperature control, and readiness to manage potential complications. Although there is no consensus on the optimal anaesthetic approach to PMC, current literature suggests that, with appropriate planning and intraoperative vigilance, safe anaesthesia is achievable.

Indexed as

anaesthesia for neuromuscular disorderscongenital neuromuscular disordereulenburg diseaseparamyotonia congenitapmc

Identifiers

PMID41164065
PMCPMC12560062

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.