Evidence map›Paper›PMID 41163996›Full record

ArticleActa naturae

Ortho- and Meta-monochlorinated Biphenyls Suppress Humoral Immunity and Exert Toxic Effects on Mouse Liver Cells.

D O Egorova, S V Gein, N A Korolev, N P Loginova

Abstract read
In one paragraph

Article in Acta naturae. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

D O EgorovaPerm Federal Research Center, Ural Branch of the Russian Academy of Sciences (PFRC UB RAS), Perm, 614990 Russia.
S V GeinPerm Federal Research Center, Ural Branch of the Russian Academy of Sciences (PFRC UB RAS), Perm, 614990 Russia.
N A KorolevPerm Federal Research Center, Ural Branch of the Russian Academy of Sciences (PFRC UB RAS), Perm, 614990 Russia.
N P LoginovaE.A. Vagner Perm State Medical University, Perm, 614990 Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Widespread environmental contamination with polychlorinated biphenyls (PCBs) leads to serious health problems for humans and animals. Our main focus should be on studying the negative effects of exposure to medium- and highly chlorinated PCBs in the human body. There is limited information on the impact of low-chlorinated biphenyls containing 1-2 substituents per molecule on the functions of mammalian organs and systems. Under natural conditions, PCBs can undergo bacterial degradation; the resulting compounds belong to a group of secondary pollutants and are considered hazardous to the environment. Because of limited research, the question regarding the impact of mono-substituted chlorobiphenyl congeners, as well as the products of their biotransformation, remains open. In the presented work, the effects of

Indexed as

biodegradationhepatocyteshumoral immunityleukocytesmonochlorinated biphenyls

Identifiers

PMID41163996
PMCPMC12560052

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.