ArticleNeurosurgery practice2025
Acute Ischemic Stroke and Endovascular Thrombectomy During COVID-19 Pandemic: A Nationwide Analysis.
Article in Neurosurgery practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND AND
objectivesInfection with COVID-19 may be linked to both higher rates of severe strokes and strokes in younger patients through distinct pathophysiological processes. This study aims to investigate characteristics and outcomes in COVID-19-related acute ischemic stroke (AIS) and endovascular thrombectomy (EVT) included in the National Inpatient Sample database.
methodsThis is a retrospective population-based observational study that includes all patients with COVID-19 and patients with AIS with COVID-19 who underwent EVT and were admitted to hospitals included in the US National Inpatient Sample between 2020 and 2021. Primary outcomes include age difference and difference in cardiovascular risk factors between patients with AIS with and without COVID-19 and EVT patients with and without COVID-19. Secondary outcomes include rates of favorable hospital outcome (defined as discharge to home or acute rehabilitation facility), in-hospital mortality, and the length of hospital stay.
resultsA total of 1 381 039 patients with AIS were included. A total of 58 525 had a COVID-19 diagnosis. A total of 83 650 patients underwent EVT, and 3075 of these patients were diagnosed with COVID-19. The mean age for patients with COVID-19 with AIS was lower (67.55 vs 69.40 years;
conclusionThis analysis demonstrates that patients with AIS and concomitant COVID-19 infection were younger, with fewer cardiovascular risk factors, and disproportionately Black and Hispanic, with worse neurological deficit and worse hospital outcome.
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