Evidence map›Paper›PMID 41163974›Full record

ArticlePrecision radiation oncology2025

Consensus statement on the exploration of clinical translation and application of electron ultra-high dose rate FLASH radiotherapy.

Hui Luo, Chengliang Yang, Jinbo Yue, Hong Ge

Abstract read
In one paragraph

Article in Precision radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Radiation oncology at a new frontier: Hotspots, challenges, and emerging advances.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. A Feasibility Study of Preclinical Ocular X-Ray FLASH Radiation Therapy.International journal of radiation oncology, biology, physics · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hui LuoDepartment of Radiation Oncology The Affiliated Cancer Hospital of Zhengzhou University Zhengzhou China.ORCID https://orcid.org/0000-0003-2149-6546
Chengliang YangDepartment of Radiation Oncology The Affiliated Cancer Hospital of Zhengzhou University Zhengzhou China.
Jinbo YueDepartment of Radiation Oncology Shandong Cancer Hospital Jinan China.ORCID https://orcid.org/0000-0002-5768-8622
Hong GeDepartment of Radiation Oncology The Affiliated Cancer Hospital of Zhengzhou University Zhengzhou China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultra-high dose rate FLASH Radiotherapy (FLASH-RT) has attracted wide attention because the well-known FLASH effect and the extremely short irradiation time. During FLASH-RT, high radiation doses and dose rate (usually thousands of times compared with conventional radiotherapy (CONV-RT)) are delivered to the tumor area. This novel irradiation technique shows a reduction of normal tissue injury (20-40%) in comparison to CONV-RT. Meanwhile, FLASH-RT maintaining comparable tumor killing effect as CONV-RT. With the progress of basic research on FLASH-RT in reducing radiation-induced injury to normal tissues, clinical trials of FLASH-RT have been carried out across the world. To date, there is no consensus in China focused on the exploration of clinical transformation and application of electron FLASH-RT. Therefore, the China Anti-Cancer Association Radiation Oncology Committee and the Chinese Medical Doctor Association Radiation Oncology Physician Committee gathered a group of experts together to develop this consensus statement. The authors discuss their current views on electron FLASH-RT, demonstrate the unresolved questions, provide insights for the further application of this technology in clinical practice.

Indexed as

clinical applicationConsensus statementelectron FLASH radiotherapytransformation

Identifiers

PMID41163974
PMCPMC12559927

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.