ArticleAnnals of thoracic surgery short reports2025
Outcomes of Infant Cardiac Surgery Using Institutional vs Commercial Cardioplegia Solution: A Comparative Analysis.
Article in Annals of thoracic surgery short reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Background: This study assessed postoperative outcomes by using markers of myocardial injury in infants who received del Nido vs institutional cardioplegia solution. Methods: Eighty-five infants undergoing cardiac surgery were enrolled (del Nido, n = 45; institutional, n = 40). Primary outcomes included serum troponin I, creatine kinase myocardial band (CK-MB), and heart fatty acid-binding protein on cardiothoracic intensive care unit (CTICU) admission and at 6, 12, and 24 hours postoperatively. Secondary outcomes included vasoactive inotropic score, arrhythmias, ventricular ejection fraction, ventilation hours, CTICU hours, hospital length of stay, and mortality. Results: Patients receiving del Nido cardioplegia solution were older (174 days vs 105 days) and had higher body weight (5.95 kg vs 5.05 kg). They received greater cardioplegia volume and had longer bypass times. The del Nido cohort showed higher initial postoperative troponin I (1.53 times at admission; Conclusions: The del Nido cardioplegia was associated with higher initial postoperative troponin I and CK-MB levels in infant cardiac surgery patients. However, no significant clinical outcome differences were found between the 2 solutions.
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