Evidence map›Paper›PMID 41163880›Full record

ArticleAnnals of thoracic surgery short reports2025

Aortic Valve Repair for Severe Commissural Leaflet Defects Using Aortic Wall Patches.

Alexander P Nissen, Melissa M Levack, Vinay Badhwar, W Brent Keeling, J Scott Rankin

Abstract read
In one paragraph

Article in Annals of thoracic surgery short reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexander P NissenDivision of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, Georgia.
Melissa M LevackDivision of Cardiothoracic Surgery, Centura Health, Denver, Colorado.
Vinay BadhwarDepartment of Cardiovascular and Thoracic Surgery, West Virginia University, Morgantown West Virginia.
W Brent KeelingDivision of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, Georgia.
J Scott RankinDepartment of Cardiovascular and Thoracic Surgery, West Virginia University, Morgantown West Virginia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In patients with aortic insufficiency, annular dilatation often accompanies valve incompetence, necessitating annuloplasty. However, primary leaflet defects also are common, and when found unexpectedly at the time of planned repair, inadequate leaflet tissue often prompts prosthetic valve replacement. A method for achieving stable repair for severe leaflet deficiencies would be useful. Methods: In this report, major leaflet defects due to ruptured large fenestrations were encountered in 2 patients, the first repaired with extensive plication, which failed. In the second patient, the defect was reconstructed using an autologous aortic wall patch. After geometric annuloplasty, the aortic wall strip was sutured with interrupted 6-0 sutures from the nodulus to the commissural top, with the intima facing coaptation. Leaflet free-edge length was adjusted to match the other normal leaflets at approximately reconstructed annular diameter x 1.5. Results: In the aortic wall patch patient, grade 4 preoperative aortic insufficiency fell to zero after repair, and the patient is doing well with continued excellent echo parameters at 1 year postoperatively. Conclusions: As a leaflet substitute during aortic valve repair, aortic wall patches seem to provide an excellent solution to managing severe leaflet deficiencies.

Identifiers

PMID41163880
PMCPMC12559602

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.