Evidence map›Paper›PMID 41163870›Full record

ArticleAnnals of thoracic surgery short reports2025

Systemic Anticoagulation at Discharge in Cardiac Surgical Patients With Postoperative Atrial Fibrillation: A Statewide Cohort Study.

Michael Mazzeffi, Jared Beller, Alex Wisniewski, Akram Zaaqoq, Jonathan Curley, Ramesh Singh, Abdulla Damluji, Mohammed Quader, Michael Kontos, Mark Joseph and 6 more

Abstract read
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In one paragraph

Article in Annals of thoracic surgery short reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Michael MazzeffiDepartment of Anesthesiology, University of Virginia, Charlottesville, Virginia.
Jared BellerDivision of Cardiothoracic Surgery, Department of Surgery, University of Virginia, Charlottesville, Virginia.
Alex WisniewskiDivision of Cardiothoracic Surgery, Department of Surgery, University of Virginia, Charlottesville, Virginia.
Akram ZaaqoqDepartment of Anesthesiology, University of Virginia, Charlottesville, Virginia.
Jonathan CurleyDepartment of Anesthesiology, University of Virginia, Charlottesville, Virginia.
Ramesh SinghDivision of Cardiothoracic Surgery, Department of Surgery, INOVA Heart and Vascular Institute, Fairfax, Virginia.
Abdulla DamlujiINOVA Center for Outcomes Research, INOVA Heart and Vascular Institute, Fairfax, Virginia.
Mohammed QuaderDivision of Cardiothoracic Surgery, Department of Surgery, Virginia Commonwealth University, Richmond, Virginia.
Michael KontosDivision of Cardiology, Department of Medicine, Virginia Commonwealth University, Richmond, Virginia.
Mark JosephDivision of Cardiothoracic Surgery, Department of Surgery, Virginia Tech Carilion School of Medicine, Roanoke, Virginia.
Raymond StrobelDivision of Cardiothoracic Surgery, Department of Surgery, University of Virginia, Charlottesville, Virginia.
Clifford E FonnerVirginia Cardiac Services Quality Initiative, South Riding, Virginia.
Nicholas TemanDivision of Cardiothoracic Surgery, Department of Surgery, University of Virginia, Charlottesville, Virginia.
Kenneth C BilchickDivision of Cardiology, Department of Medicine, University of Virginia, Charlottesville, Virginia.
Ourania PreventzaDivision of Cardiothoracic Surgery, Department of Surgery, University of Virginia, Charlottesville, Virginia.
Kenan YountDivision of Cardiothoracic Surgery, Department of Surgery, University of Virginia, Charlottesville, Virginia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Direct oral anticoagulants (DOACs) have changed systemic anticoagulation practice for atrial fibrillation. We hypothesized that DOACs are increasingly used for postoperative atrial fibrillation after cardiac surgery, and associated with fewer anticoagulation-related complications compared with warfarin. Methods: We performed a retrospective cohort study of patients undergoing coronary artery bypass grafting, valve surgery, or combined coronary artery bypass grafting/valve surgery from 2011 through 2023 using a statewide database. The primary outcome was systemic anticoagulation at discharge in patients with postoperative atrial fibrillation. Secondary outcomes were length of hospital stay, unplanned readmission for anticoagulation-related complications, and unplanned readmission for stroke or cardiac tamponade. Results: The incidence of postoperative atrial fibrillation was 23.8% among 45,258 patients who met study inclusions, and 32.5% of patients with postoperative atrial fibrillation were discharged on systemic anticoagulation. DOAC prescription at discharge for patients with postoperative atrial fibrillation increased from 1.9% in 2011 to 32.3% in 2023. Postoperative length of stay was shorter in those who received a DOAC vs warfarin (7 vs 9 days, Conclusions: Systemic anticoagulation was prescribed for approximately a third of patients with postoperative atrial fibrillation after cardiac surgery. There was an increase in DOAC use over time, which appears to be associated with fewer anticoagulation-related complications.

Identifiers

PMID41163870
PMCPMC12559601

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.