ArticleSaudi journal of medicine & medical sciences
Barriers to Rapid Stroke Thrombolysis at a Large Tertiary Care Hospital in Riyadh, Saudi Arabia.
Article in Saudi journal of medicine & medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Awareness of Stroke Symptoms, Risk Factors, and Utilization of Neuroradiology Services Among the General Public in Saudi Arabia.Healthcare (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Acute ischemic stroke (AIS) is a major cause of mortality and disability worldwide, requiring rapid intervention to prevent brain damage. Timely thrombolytic therapy with tissue plasminogen activator (tPA) is essential but often underutilized due to barriers in treatment delivery. Objectives: This study aimed to identify barriers impacting the timely administration of thrombolytic therapy in AIS patients at a major tertiary care hospital in Riyadh, Saudi Arabia. Methods: This retrospective cohort study included adult patients with AIS who were admitted to the Emergency Department (ED) of King Abdulaziz Medical City, Riyadh, between November 2015 and March 2023. Patient demographics, clinical characteristics, and records on ED arrival time were reviewed to identify barriers to thrombolysis. Results: A total of 576 patients were included in the study (mean age: 64 ± 13 years; male: 65%). The mean National Institutes of Health Stroke Scale score at presentation to the ED was 7.3, indicating a moderate level of severity among stroke patients. The study found that delayed ED arrival (77%) and current anticoagulant use (34%) were the main barriers to thrombolysis. The most common symptoms were weakness (77%), slurred speech (62%), and facial droop (28%). Only 10% of patients received thrombolytic therapy, of which 70% received an appropriately calculated dose. Conclusion: Delayed emergency department arrival and recent use of anticoagulants significantly impact timely thrombolysis for acute ischemic stroke in Saudi Arabia. Prospective multi-center studies are recommended to further explore these barriers across varied healthcare settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.