Evidence map›Paper›PMID 41163776›Full record

ArticleDementia & neuropsychologia2025

Trends in Alzheimer's disease mortality in Espírito Santo, Brazil: a time series study.

Ana Luisa Horsth, Marcelo Matieli da Silva, Jéssica Barreto Ribeiro Dos Santos, Michael Ruberson Ribeiro da Silva

Abstract read
In one paragraph

Article in Dementia & neuropsychologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ana Luisa HorsthUniversidade Federal do Espírito Santo, Centro de Ciências Exatas, Naturais e da Saúde, Grupo de Avaliação, Tecnologia e Economia em Saúde, Alegre ES, Brazil.ORCID https://orcid.org/0000-0001-7556-6584
Marcelo Matieli da SilvaUniversidade Federal do Espírito Santo, Centro de Ciências Exatas, Naturais e da Saúde, Grupo de Avaliação, Tecnologia e Economia em Saúde, Alegre ES, Brazil.ORCID https://orcid.org/0009-0004-6645-1768
Jéssica Barreto Ribeiro Dos SantosUniversidade Federal do Espírito Santo, Centro de Ciências Exatas, Naturais e da Saúde, Grupo de Avaliação, Tecnologia e Economia em Saúde, Alegre ES, Brazil.ORCID https://orcid.org/0000-0002-5528-0658
Michael Ruberson Ribeiro da SilvaUniversidade Federal do Espírito Santo, Centro de Ciências Exatas, Naturais e da Saúde, Grupo de Avaliação, Tecnologia e Economia em Saúde, Alegre ES, Brazil.ORCID https://orcid.org/0000-0003-2550-7249

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is one of the leading causes of dementia in older adults and is associated with a significant increase in the number of deaths globally. Objective: This study analyzed mortality from AD in the state of Espírito Santo, Brazil, between 2013 and 2022. Methods: This ecological time series study used data from the Mortality Information System and the Brazilian Institute of Geography and Statistics, identifying deaths per the International Classification of Diseases 10 Results: A total of 6,083 deaths from AD were identified during the study period. We observed a progressive increase in the absolute number of deaths, up from 375 in 2013 to 802 in 2022, as well as in the mortality rate, which rose from 9.77 to 21.02 per 100 thousand inhabitants. We identified a statistically significant upward trend (p<0.001), with a mean annual increase of 49.68 deaths (β Conclusion: The study showed a significant increase in mortality from AD in Espírito Santo over the years, reinforcing the importance of preventive strategies aimed at health care and healthy aging.

Indexed as

Alzheimer DiseaseEpidemiologyMortalityPublic Health

Identifiers

PMID41163776
PMCPMC12561170

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.