ArticleJournal of medical physics
Comparative Dosimetric Analysis of Three Radiotherapy Fractionation Schedules in Synchronous Bilateral Breast Cancer: Evaluation of Lung and Heart Normal Tissue Complication Probability.
Article in Journal of medical physics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: This study aims to evaluate and compare the impact of dosimetric parameters on lungs, heart, and associated normal tissue complication probability (NTCP) values among three different right (RT) prescription doses in patients with synchronous bilateral breast cancer (SBBC). Materials and Methods: For retrospectively selected five patients diagnosed with SBBC, volumetric-modulated arc therapy treatment plans were developed across three different fractionation schedules: ultra-hypofractionated (UHF) (26 Gy/5#), hypofractionated (HF) (40.05 Gy/15#), and conventional fractionation (CF) (50 Gy/25#). The dosimetric parameters, including conformity index (CI), coverage index, homogeneity index, D95%, and V105%, along with the doses to organ at risk (OAR) (lung, heart, left anterior descending artery), were assessed. NTCP models were used to estimate the risks of complications. Results: The dose-volume parameters for OAR exhibited a parabolic trend (χ Conclusion: This study provides evidence in favor of hypofractionation for breast cancer radiotherapy, showing promise in minimizing normal tissue side effects.
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