Evidence map›Paper›PMID 41163729›Full record

ReviewNeurosurgery practice2025

Departments of Neurosurgery are Leaders in Highly Cited Glioblastoma Research.

Masih Tazhibi, Rishab Ramapriyan, Parker Kotlarz, Samuel J Steuart, Adrian Kalaw, Mona Tazhibi, Bob S Carter, E Antonio Chiocca, Brian V Nahed, William T Curry and 1 more

Abstract readReview
In one paragraph

Review in Neurosurgery practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Masih TazhibiDepartment of Neurological Surgery, Mass General Brigham, Boston, Massachusetts, USA.
Rishab RamapriyanDepartment of Neurological Surgery, Mass General Brigham, Boston, Massachusetts, USA.
Parker KotlarzDepartment of Neurological Surgery, Mass General Brigham, Boston, Massachusetts, USA.
Samuel J SteuartDepartment of Neurological Surgery, Mass General Brigham, Boston, Massachusetts, USA.
Adrian KalawDepartment of Neurological Surgery, Mass General Brigham, Boston, Massachusetts, USA.
Mona TazhibiUniversity of California, Berkeley, Berkeley, California, USA.
Bob S CarterDepartment of Neurological Surgery, Mass General Brigham, Boston, Massachusetts, USA.
E Antonio ChioccaDepartment of Neurological Surgery, Mass General Brigham, Boston, Massachusetts, USA.
Brian V NahedDepartment of Neurological Surgery, Mass General Brigham, Boston, Massachusetts, USA.
William T CurryDepartment of Neurological Surgery, Mass General Brigham, Boston, Massachusetts, USA.
Bryan D ChoiDepartment of Neurological Surgery, Mass General Brigham, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-5090-2470

Funding

Medical Scientist Training ProgramT32GM144273 · NIGMS · HARVARD MEDICAL SCHOOL · PI David Shumway Jones, Jacqueline A. Lees · 2022 to 2026
$14.7M
Bioactivity of CAR T cells secreting T cell engager-anitbodies in humans with glioblastomaR01CA294071 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Bryan Choi, Marcela Valderrama Maus · 2024 to 2026
$3.1M
NCI NIH HHS R01 CA294071NIGMS NIH HHS T32 GM144273
6 · The paper itself

Abstract

BACKGROUND AND

objectivesWe conducted a bibliometric analysis of highly cited glioblastoma (GBM) research published between 2013 and 2023, focusing on identifying key academic departments and institutional contributions within the United States.

methodsA comprehensive search of the Web of Science database was performed to identify "highly cited articles," defined as those receiving the top one percent for citations within their field each year. Primary research articles authored by researchers at U.S. institutions between 2013 and 2023 were included. We categorized articles by subject area and departmental contributions and used VOSviewer and R for data visualization and analysis.

resultsOverall, 169 highly cited GBM articles were included in the study. Neurosurgery emerged as the largest contributing department type, accounting for 28.4% (48/169) of highly cited articles. This was followed by departments of biology or genetics (22/169), neurology or neuro-oncology (16/169), and radiology or radiation oncology (13/169). "Immunology and Immunotherapy" was the dominant subject area for highly cited papers, with 50.3% (85/169) investigating the immunological landscape of GBM or using immunotherapy as the primary treatment modality. Keyword analysis demonstrated a thematic shift toward tumor biology and immune-based therapies over the study period, highlighting emerging trends in GBM research.

conclusionDepartments of neurosurgery have established themselves as key drivers in GBM research. The prominence of tumor biology and immunotherapy reflect broader shifts in treatment approaches. Continued support for neurosurgical departments and targeted funding initiatives is essential for advancing GBM research, fostering innovation, and improving patient outcomes in this challenging field.

Indexed as

Bibliometric analysesGlioblastomaNeurosurgery

Identifiers

PMID41163729
PMCPMC12560700

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.