Evidence map›Paper›PMID 41163647›Full record

ArticleNeurosurgery practice2025

Comparison of Machine Learning Methods to Predict Early Mortality After Evacuation of Chronic Subdural Hematoma.

Trenton A Line, Anoop S Chinthala, Barnabas Obeng-Gyasi, Gordon Mao, Jamie L Bradbury, Aditya Mittal, Jan Vargas, Ryan T Kellogg, Enyinna Nwachuku, David O Okonkwo and 1 more

Abstract read
In one paragraph

Article in Neurosurgery practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Trenton A LineDepartment of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID https://orcid.org/0000-0003-3443-6964
Anoop S ChinthalaDepartment of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Barnabas Obeng-GyasiDepartment of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Gordon MaoDepartment of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Jamie L BradburyDepartment of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Aditya MittalDepartment of Neurosurgery, University of Pittsburgh Medical Center Medical School, Pittsburgh, Pennsylvania, USA.
Jan VargasDivision of Neurosurgery, PRISMA Health, Greenville, South Carolina, USA.
Ryan T KelloggDepartment of Neurosurgery, University of Virginia, Charlottesville, Virginia, USA.
Enyinna NwachukuDepartment of Neurosurgery, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
David O OkonkwoDepartment of Neurosurgery, UPMC Healthcare System, Pittsburgh, Pennsylvania, USA.
Matthew PeaseDepartment of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesWe developed a series of machine learning models to predict early mortality after chronic subdural hematoma (cSDH) evacuation.

methodsWe retrospectively collected patients treated surgically for cSDH at 4 level 1 trauma centers (2009-2021). Previously, we developed a deep learning segmentation tool to automatically calculate preoperative and postoperative cSDH volumes. Using cSDH volumes and clinical information, we developed 6 machine learning models including logistic regression (LR), support vector machine, neural network (NN), decision tree (DT), Naïve Bayes, and XGBoost to predict 30-day mortality after surgery. We applied least absolute shrinkage and selection operator regression to select a subset of predictors for consistent model input. To account for class imbalance, we used synthetic minority oversampling technique. We used 10-fold cross validation to evaluate model performance.

resultsWe included 731 patients. Our final models included age, admission Glasgow Coma Scale, unilateral/bilateral hematoma, antiplatelet status, platelet count, preoperative volume, and method of surgical evacuation. The 30-day mortality rate was 7.5%. Overall, our models demonstrated moderate discriminative ability with area under the receiver operating characteristics curves (AUCs) ranging from 0.64 for DT (95% CI: 0.56-0.72) to 0.75 for LR (95% CI: 0.69-0.81). AUC for DT was significantly lower than LR (

conclusionThe LR model demonstrated the best performance of discriminative ability, balanced accuracy, and recall, whereas DT modeling performed worst. Using an automated segmentation software, our models demonstrate an ability to identify patients at high risk of mortality after treatment for cSDH.

Indexed as

Artificial intelligenceChronic subdural hematomaMachine learningMortalityPredictive modeling

Identifiers

PMID41163647
PMCPMC12560736

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.