Evidence map›Paper›PMID 41163645›Full record

ArticleCase reports in endocrinology2025

Resistance to Thyroid Hormone Beta and Coexisting Thyroid Disease: Diagnostic and Therapeutic Challenges Illustrated by Two Cases.

Sara Ribeiro, Ana Varela, Joana Queirós

Abstract readCase Reports
In one paragraph

Article in Case reports in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sara RibeiroDepartment of Endocrinology, Diabetes and Metabolism, São João Local Health Unit, Porto, Portugal.ORCID https://orcid.org/0009-0009-1413-5591
Ana VarelaDepartment of Endocrinology, Diabetes and Metabolism, São João Local Health Unit, Porto, Portugal.ORCID https://orcid.org/0000-0002-2759-8191
Joana QueirósDepartment of Endocrinology, Diabetes and Metabolism, São João Local Health Unit, Porto, Portugal.ORCID https://orcid.org/0009-0005-7026-4794

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resistance to thyroid hormone (RTH) is a rare clinical syndrome characterized by reduced tissue responsiveness to thyroid hormone (TH), typically presenting with elevated TH levels without suppression of thyrotropin (TSH). In most cases, RTH is caused by mutations in the TH receptor beta (

Indexed as

amiodarone-induced hypothyroidismHashimoto's thyroiditisindividualized treatmentresistance to thyroid hormone (RTH)thyroid dysfunction

Identifiers

PMID41163645
PMCPMC12566943

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.