Evidence map›Paper›PMID 41163623›Full record

ArticleGlobal health action2025

A decade of health research capacity building in Honduras: institutional transformation, challenges, and lessons learned.

Gustavo Fontecha, Ana Sánchez, Gabriela Matamoros, Denis Escobar, Bryan Ortiz

Abstract read
In one paragraph

Article in Global health action, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gustavo FontechaInstituto de Investigaciones en Microbiología, Facultad de Ciencias, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.ORCID 0000-0001-9756-4520
Ana SánchezDepartment of Community Health Sciences, Brock University, St. Catharines, Ontario, Canada.ORCID 0000-0002-6683-2518
Gabriela MatamorosInstituto de Investigaciones en Microbiología, Facultad de Ciencias, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.ORCID 0000-0003-2177-9765
Denis EscobarInstituto de Investigaciones en Microbiología, Facultad de Ciencias, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.ORCID 0000-0002-1188-2569
Bryan OrtizInstituto de Investigaciones en Microbiología, Facultad de Ciencias, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.ORCID 0000-0002-8328-244X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHonduras has historically faced major barriers to building a sustainable health research system, including minimal R&D investment and limited institutional infrastructure. A Canadian-funded initiative (2007-2012) established the first research-oriented MSc program, a non-clinical ethics board, and modern laboratories at the

objectiveThis article examines how health research capacity evolved between 2013 and 2025, highlighting long-term outcomes, enablers, and barriers, and situating these within a regional Central American comparison. The narrative, largely anecdotal, reflects on the experience and impact of biomedical research at UNAH, particularly through the

methodsAlumni trajectories and institutional transformations are illustrated with concrete examples. Bibliometric analysis contextualizes scientific output, complemented by broader indicators (GDP, R&D investment, tertiary education, PhDs per million) from World Bank sources.

resultsMore than 30 MSc graduates have strengthened biomedical and public health institutions, with several completing doctoral training abroad and returning to Honduras. Since its formal creation in 2014, the IIM has produced over 170 publications, representing more than 20% of UNAH's health-related output since 2012. Challenges to sustainability include chronic underinvestment (< 0.1% GDP in R&D), rigid bureaucracy, limited career pathways, and brain drain. Enablers have been international partnerships, the academic diaspora, and strong local leadership.

conclusionThe Honduran case illustrates how targeted, multi-level investment in individuals, institutions, and governance can foster long-term research capacity in resource-constrained settings, while underscoring the need for national policies, career structures, private sector engagement, and sustained international collaboration.

Indexed as

Biomedical ResearchCapacity BuildingHondurasHumansCentral Americahigher educationinternational cooperationresearch collaborationresearch personnel

Identifiers

PMID41163623
PMCPMC12576901

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.