ArticleBrain and behavior2025
Dietary Antioxidant Quality Score and Epilepsy Odds in the US Adults: A Cross-Sectional NHANES Study.
Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy and safety of antioxidants and dietary therapies for epilepsy: an umbrella meta-analysis.Frontiers in nutrition · 2025Pooled it
- Knowledge and attitudes toward epilepsy among medical students and internship doctors: a multinational cross-sectional study in Syria, Jordan, Palestine, and Libya.BMC medical education · 2026Article
- The Role of Antioxidants in the Connection Between Microbiota, Neuroinflammation and Epilepsy.Biomedicines · 2026Review
- Dietary Antioxidant Quality Score and Epilepsy Odds in the US Adults: A Cross-Sectional NHANES Study.Brain and behavior · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEpilepsy is defined by the occurrence of a minimum of two unprovoked seizures, with a temporal gap exceeding 24 h between episodes. This research aimed to ascertain the link between dietary antioxidant quality score (DAQS) and the odds of developing epilepsy.
methodsIn this cross-sectional study, utilizing data from the National Health and Nutrition Examination Survey spanning 2017-2020, binary logistic regression analyses were carried out to investigate the link between DAQS and the odds of epilepsy. We recruited a cohort of 1086 individuals with pathologically confirmed diagnoses of epilepsy with 1086 controls.
resultsThe mean age of participants was 58.26 years, with cases and controls averaging 54.26 and 62.26 years, respectively. Highest adherence to the DAQS was significantly linked to epilepsy compared to their counterparts with the lowest adherence (odds ratio [OR]: 0.76, 95% confidence interval [CI]: 0.68-0.85, p < 0.001), subgroup results revealed higher odds in those refusing education (OR: 5.6, 95% CI: 1.00-10.6, p = 0.05) and never married individuals (OR: 1.63, 95% CI: 1.22-2.18, p = 0.001). Conversely, significant reductions were observed for education levels beyond nineth grade (e.g., OR: 0.33 for high school graduates, p <0.001) and widowed participants (OR: 0.71, 95% CI: 0.56-0.91, p = 0.006). Ethnically, non-Hispanic Blacks and Asians had 36% (OR: 0.64, 95% CI: 0.44-0.94, p = 0.024) and 65% (OR: 0.35, 95% CI: 0.20-0.60, p<0.001) lower odds than Mexican Americans.
conclusionOur findings suggest a modest inverse association between higher DAQS and epilepsy odds; however, due to the cross-sectional design, no causal inference can be made. Sociodemographic factors appear to modify this association and should be considered in future research.
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