Evidence map›Paper›PMID 41163199›Full record

ArticleParticle and fibre toxicology2025

Seasonal PM

Stephanie A Brocke, Timothy Smyth, Hong Dang, Adam Speen, Yong Ho Kim, Cara Christianson, Kasey Kovalcik, Joseph Patrick Pancras, Michael Hays, Zhen An and 2 more

Abstract read
In one paragraph

Article in Particle and fibre toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Frontiers in microbiology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Stephanie A Brocke *Curriculum in Toxicology and Environmental Medicine, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Timothy Smyth *Curriculum in Toxicology and Environmental Medicine, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Hong DangMarsico Lung Institute, University of North Carolina, Chapel Hill, NC, USA.
Adam SpeenCenter for Environmental Medicine, Asthma, and Lung Biology, University of North Carolina, Chapel Hill, NC, USA.
Yong Ho KimOffice of Research and Development, United States Environmental Protection Agency, Research Triangle Park, NC, USA.
Cara ChristiansonOffice of Research and Development, United States Environmental Protection Agency, Research Triangle Park, NC, USA.
Kasey KovalcikOffice of Research and Development, United States Environmental Protection Agency, Research Triangle Park, NC, USA.
Joseph Patrick PancrasOffice of Research and Development, United States Environmental Protection Agency, Research Triangle Park, NC, USA.
Michael HaysOffice of Research and Development, United States Environmental Protection Agency, Research Triangle Park, NC, USA.
Zhen AnSchool of Public Health, Xinxiang Medical University, Xinxiang, Henan Province, People's Republic of China.
Weidong WuSchool of Public Health, Xinxiang Medical University, Xinxiang, Henan Province, People's Republic of China.
Ilona JaspersDepartment of Pediatrics, School of Medicine, University of North Carolina, Chapel Hill, NC, USA. ilona_jaspers@med.unc.edu.

Funding

TOXICOLOGYT32ES007126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ILONA JASPERS, Bernard E. Weissman · 1985 to 2026
$13.0M
UNC Research Training Program in Respiratory Diseases and Critical CareT32HL166141 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Richard Charles Boucher, Claire M Doerschuk · 2023 to 2026
$2.2M
PM exposure and changes in respiratory host defense responsesR01ES031173 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ALEXIS, NEIL · 2020 to 2024
$1.2M
NHLBI NIH HHS T32 HL166141NIEHS NIH HHS R01 ES031173NIEHS NIH HHS T32 ES007126U.S. Environmental Protection Agency CR 84033801
6 · The paper itself

Abstract

backgroundAir pollution, specifically fine particulate matter (PM

resultsSummer and fall PM

conclusionsSeasonal variations in PM2.5 composition during winter, spring, and fall-coinciding with influenza season-likely enhance pro-inflammatory responses to viral infection, with early inflammation contributing to worsened pathogenesis.

Indexed as

Air PollutantsEpithelial CellsInfluenza A Virus, H1N1 SubtypeInfluenza, HumanParticulate MatterSeasonsCells, CulturedChinaFemaleHumansMaleParticle SizeAir PollutantsParticulate Matter

Identifiers

PMID41163199
PMCPMC12570438

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.