Evidence map›Paper›PMID 41163179›Full record

ArticleJournal of nanobiotechnology2025

Transcranial and precise optical neuromodulation mediated by NIR photoactive nanosheets.

Deqi Yang, Ya Zhang, Yun Yuan, Beibei Peng, Bingfang Wang, Qinjuan Ren, Zhiqiang Chang, Shuai Liu, Yin Fang

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Deqi Yang *Research Center for Translational Medicine, Medical Innovation Center, State Key Laboratory of Cardiology, The Institute for Biomedical Engineering & Nano Science, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200092, China.
Ya Zhang *Research Center for Translational Medicine, Medical Innovation Center, State Key Laboratory of Cardiology, The Institute for Biomedical Engineering & Nano Science, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200092, China. yazhang@tongji.edu.cn.
Yun Yuan *Research Center for Translational Medicine, Medical Innovation Center, State Key Laboratory of Cardiology, The Institute for Biomedical Engineering & Nano Science, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200092, China.
Beibei PengShanghai Changning Mental Health Center, Affiliated Mental Health Center of East China Normal University, Shanghai, 200062, China.
Bingfang WangResearch Center for Translational Medicine, Medical Innovation Center, State Key Laboratory of Cardiology, The Institute for Biomedical Engineering & Nano Science, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200092, China.
Qinjuan RenResearch Center for Translational Medicine, Medical Innovation Center, State Key Laboratory of Cardiology, The Institute for Biomedical Engineering & Nano Science, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200092, China.
Zhiqiang ChangResearch Center for Translational Medicine, Medical Innovation Center, State Key Laboratory of Cardiology, The Institute for Biomedical Engineering & Nano Science, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200092, China.
Shuai LiuShanghai Changning Mental Health Center, Affiliated Mental Health Center of East China Normal University, Shanghai, 200062, China. sliu@psy.ecnu.edu.cn.
Yin FangResearch Center for Translational Medicine, Medical Innovation Center, State Key Laboratory of Cardiology, The Institute for Biomedical Engineering & Nano Science, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200092, China. yin_fang@tongji.edu.cn.

Funding

National Natural Science Foundation of China 82001960National Natural Science Foundation of China 82302404National Natural Science Foundation of China 82471572Science and Technology Commission of Shanghai Municipality 21ZR1465200Shanghai Municipal Health Commission 20234Y0115Shanghai Municipal Science and Technology Major Project 2021SHZDZX0100
6 · The paper itself

Abstract

Remote modulation of specific neurons is critical for neural circuit dissection and neurological disease therapy. Traditional neuromodulation strategies applying electrodes and external stimuli may suffer from invasive injuries and insufficient spatiotemporal resolution, respectively. Herein, transcranial optical neuromodulation with precise spatiotemporal control was realized by establishing a nanophotonic neural interface, where the polyethylene glycol-modified two-dimensional Ti

Indexed as

NanostructuresAction PotentialsAnimalsBrainInfrared RaysMaleMiceNeuronsPolyethylene GlycolsTitaniumPolyethylene GlycolsTitaniumMXeneNeuromodulationNeuronal action potentialsPhotoactive nanosheetsTranscranial optical stimulation

Identifiers

PMID41163179
PMCPMC12574063

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.