Evidence map›Paper›PMID 41163099›Full record

ReviewCritical care (London, England)2025

Towards optimised nutrition therapy after critical illness: a position statement and research framework by the global research initiative on post-intensive care nutrition (GRIP) consortium.

Zenzi Rosseel, Noortje M P Overwater, Maridi Aerts, Lee-Anne S Chapple, Dechang Chen, Krista L Haines, Jiao Liu, Imre W K Kouw, Lu Ke, Claude Pichard and 8 more

Abstract readReviewConsensus Statement
In one paragraph

Review in Critical care (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Nutritional Recovery After Critical Illness: A Qualitative Study of ICU Survivors' Experiences After Hospital Discharge.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Zenzi Rosseel *Brussels Health Campus, Faculty of Medicine and Pharmacy, Vitality Research Group, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, Brussels, 1090, Belgium. Zenzi.rosseel@uzbrussel.be.
Noortje M P Overwater *Division of Human Nutrition and Health, Nutritional Biology, Wageningen University & Research, HELIX (Building 124), Stippeneng 4, Wageningen, 6708 WE, the Netherlands.
Maridi AertsBrussels Health Campus, Faculty of Medicine and Pharmacy, Vitality Research Group, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, Brussels, 1090, Belgium.
Lee-Anne S ChappleAustralian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Dechang ChenDepartment of Critical Care Medicine, School of Medicine, Shanghai Jiaotong University, Affiliated Ruijin Hospital, Shanghai, China.
Krista L HainesDivision of Trauma, Critical Care and Acute Care Surgery, Department of Surgery, Duke University School of Medicine, Durham, NC, USA.
Jiao LiuDepartment of Critical Care Medicine, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210002, Jiangsu, China.
Imre W K KouwDivision of Human Nutrition and Health, Nutritional Biology, Wageningen University & Research, HELIX (Building 124), Stippeneng 4, Wageningen, 6708 WE, the Netherlands.
Lu KeDepartment of Critical Care Medicine, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210002, Jiangsu, China.
Claude PichardNutrition Unit, Geneva University Hospital, Geneva, Switzerland.
Emma J RidleyAustralian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Pierre SingerHerzliya Medical Center and Lab on Computerized Decision Making, Dina Recanati School of Medicine, ICU, Reichman University, Herzliya, Israel.
Dan L WaitzbergGastroenterology Dept., University of Sao Paulo - Sao Paulo Brazil, São Paulo, LIM-35, SP, Brazil.
Weiqin LiDepartment of Critical Care Medicine, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210002, Jiangsu, China.
Paul E WischmeyerDivision of Critical Care, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
Youzhong AnDepartment of Critical Care Medicine United Family Healthcare Group (Beijing), Peking University People's Hospital (PKUPH), Beijing, China.
Arthur R H van ZantenDivision of Human Nutrition and Health, Nutritional Biology, Wageningen University & Research, HELIX (Building 124), Stippeneng 4, Wageningen, 6708 WE, the Netherlands.
Elisabeth De WaeleBrussels Health Campus, Faculty of Medicine and Pharmacy, Vitality Research Group, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, Brussels, 1090, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile mortality for critically ill patients has decreased, many survivors face persistent physical, cognitive, and psychological impairments, collectively known as post-intensive care syndrome, which significantly reduce health-related quality of life (HRQoL). Nutrition is a crucial component of recovery, yet evidence-based strategies for post-intensive care unit (ICU) nutritional management remain underdeveloped.

methodsThe Global Research Initiative on Post-ICU Nutrition (GRIP) was established to address this gap by advancing research, education, and clinical practice in post-ICU nutrition. International experts in the field of critical care nutrition were invited to a diagnostic matrix meeting, to develop a definition of post-ICU patients relevant to GRIP, discuss emerging evidence regarding post-ICU nutritional management, and identify core research domains to guide future research.

resultsThe consortium consensus was achieved. A post-ICU patient is defined as any adult patient who has been admitted to an ICU for more than 48 h and is in the post-ICU recovery phase, which begins after the first ICU discharge and continues for up to one year, regardless of hospital length of stay, readmissions, or discharge destination. Ten core nutrition research domains were identified, including: (1) pathophysiology of post-ICU recovery, (2) phenotyping and personalised nutrition strategies, (3) timing and delivery of nutrition, (4) nutritional intake monitoring and optimisation, (5) nutrition interventions and effectiveness, (6) long-term functional and health-related quality of life outcomes, (7) digital tools and remote monitoring, (8) education and healthcare professional engagement, (9) implementation science and system integration, and (10) patient and family involvement.

conclusionGRIP envisions a future in which patients post-ICU receive personalised, timely, and effective nutritional care to enhance recovery, reduce complications, and improve long-term HRQoL. By identifying knowledge gaps, initiating targeted research projects, and supporting global educational efforts, GRIP aims to generate robust evidence, foster international collaboration, and strengthen clinical capacity to improve global post-ICU nutritional care.

Indexed as

Critical IllnessNutrition TherapyCritical CareHumansIntensive Care UnitsQuality of LifeGlobal research initiative on Post-ICU nutritionICUNutritionPost-ICU patient

Identifiers

PMID41163099
PMCPMC12574275

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.