Evidence map›Paper›PMID 41163072›Full record

ArticleEuropean journal of medical research2025

Pressure-strain loop evaluation of myocardial work in patients with coronary artery disease and preserved left ventricular ejection fraction: a retrospective study based on propensity score matching.

Xiaolong Yu, Ruixiao Song, Jun Xu, Gaojun Cai, Zun Li, Jing Xi

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Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Xiaolong Yu *Department of Ultrasonics, Wujin Hospital Affiliated With Jiangsu University, Changzhou, Jiangsu, China.
Ruixiao Song *Department of Ultrasonics, Wujin Hospital Affiliated With Jiangsu University, Changzhou, Jiangsu, China.
Jun XuDepartment of Ultrasonics, Wujin Hospital Affiliated With Jiangsu University, Changzhou, Jiangsu, China.
Gaojun CaiDepartment of Cardiology, Wujin Hospital Affiliated With Jiangsu University, The Wujin Clinical College of Xuzhou Medical University, Changzhou, Jiangsu, China.
Zun LiDepartment of Ultrasonics, Changzhou West Taihu Lake Hospital, Changzhou, Jiangsu, China.
Jing XiDepartment of Ultrasonics, Wujin Hospital Affiliated With Jiangsu University, Changzhou, Jiangsu, China. xijing1007@126.com.

Funding

Medical Education Collaborative Innovation Fund of Jiangsu University No.JDYY2023078Open project of Jiangsu Key Laboratory of Labora-tory Medicine JSKLM-Y-2024-003the Changzhou High-Level Medical Talents Training Project 2022CZBJ109the Science and Technology Project (Social Development) of Wujin District No.WS202103
6 · The paper itself

Abstract

objectiveTo quantify left ventricular function changes in stable coronary artery disease (SCAD) patients with preserved left ventricular ejection fraction using left ventricular pressure-strain loop (LV-PSL) technology. And to evaluate the independent correlation between myocardial work (MW) parameters and SYNTAX score.

methodsWe enrolled 126 patients with suspected SCAD. Forty-five had significant stenosis (SYNTAX score calculated). Seventy-two without significant stenosis served as controls. LV-PSL provided global longitudinal strain (GLS) and MW parameters Including global constructive work (GCW), global wasted work (GWW), global work efficiency (GWE), global work index (GWI) Propensity score matching balanced baseline characteristics. We used paired t-tests, Wilcoxon signed-rank tests, and chi-square tests for group comparisons. Correlation analysis assessed links between SYNTAX scores and GLS/MW parameters. Receiver Operating Characteristic (ROC) curve analysis determined diagnostic performance.

resultsForty-two patient pairs were successfully matched. Significant differences (P < 0.05) were found in GLS and MW parameters between SCAD patients and controls. SCAD patients exhibited lower GCW, GWI, and GWE compared to controls (P < 0.05). Correlation analysis revealed moderate positive correlations between SYNTAX scores and GWW, and moderate negative correlations with GCW. Strong negative correlations were observed between the SYNTAX score and GWE, GWI, and GLS (P < 0.01). ROC analysis identified GWI as a strong SCAD predictor (AUC = 0.713).

conclusionLV-PSL technology effectively monitors left ventricular function and assesses disease severity in SCAD patients, offering practical guidance for clinical decision-making.

Indexed as

Coronary Artery DiseaseStroke VolumeVentricular Function, LeftAgedFemaleHumansMaleMiddle AgedPropensity ScoreRetrospective StudiesROC CurveCoronary artery diseaseLeft ventricular pressure–strain loopMyocardial workSpeckle-tracking echocardiographySYNTAX score

Identifiers

PMID41163072
PMCPMC12574053

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.