Evidence map›Paper›PMID 41162991›Full record

ArticleWorld journal of surgical oncology2025

Loss of neuromonitoring signal in thyroid surgery: predictive factors and surgical strategies.

Jérôme Houdu, Alexandre Bozec, Renaud Schiappa, Agathe Villarme, Grégoire d'Andréa, Gilles Poissonnet, Isabel Gimenez, Julie Sanglier, Danielle Benisvy, Emmanuel Chamorey and 1 more

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Article in World journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Jérôme HouduCentre Antoine Lacassagne, Institut Universitaire de la Face et du Cou, 31 avenue de Valombrose, Nice, 06107, France.
Alexandre BozecCentre Antoine Lacassagne, Institut Universitaire de la Face et du Cou, 31 avenue de Valombrose, Nice, 06107, France.
Renaud SchiappaDépartements de statistiques médicales, Centre Antoine Lacassagne, 33 av de Valombrose, Nice, 06189, France.
Agathe VillarmeCentre Antoine Lacassagne, Institut Universitaire de la Face et du Cou, 31 avenue de Valombrose, Nice, 06107, France.
Grégoire d'AndréaService d'Oto-Rhino-Laryngologie, Centre Hospitalier Universitaire de Nice, Nice, France.
Gilles PoissonnetCentre Antoine Lacassagne, Institut Universitaire de la Face et du Cou, 31 avenue de Valombrose, Nice, 06107, France.
Isabel GimenezDépartement d'anatomie pathologique, Centre Antoine Lacassagne, 33 av de Valombrose, Nice, 06189, France.
Julie SanglierDépartement d'imagerie médicale, Centre Antoine Lacassagne, 33 av de Valombrose, Nice, 06189, France.
Danielle BenisvyDépartement de médecine nucléaire, Centre Antoine Lacassagne, 33 av de Valombrose, Nice, 06189, France.
Emmanuel ChamoreyDépartements de statistiques médicales, Centre Antoine Lacassagne, 33 av de Valombrose, Nice, 06189, France.
Dorian CuliéCentre Antoine Lacassagne, Institut Universitaire de la Face et du Cou, 31 avenue de Valombrose, Nice, 06107, France. dorian.culie@nice.unicancer.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectives1- To assess the predictive factors of loss of neuromonitoring signal (LOS) during thyroid surgery and its possible impact on the risk of recurrent laryngeal nerve palsy (RLNP) and 2- to analyze the potential changes in the surgical strategy induced by LOS during surgery.

methodsThis was a retrospective analysis of the medical records of all patients who underwent hemithyroidectomy (HT) or total thyroidectomy (TT) at our institution between 2005 and 2023. Predictive factors of LOS and RLNP were evaluated via univariate and multivariate analyses.

resultsA total of 114 patients (3.4%) experienced unilateral LOS during surgery, and 54 of them developed RLNP (positive predictive value of LOS = 41%). Multivariate analysis revealed that male sex (odds ratio: OR = 2.64; 95% confidence interval: CI = 1.45–4.76) and TT (OR = 1.76; 95% CI = 1.14–2.77) were independently associated with a greater risk of LOS but had no impact on the risk of RLNP. Among the 58 patients who experienced LOS at the end of the first side in a planned TT, surgery was discontinued in 4 patients (4 with postoperative RLNP) and pursued in 48 patients (25 patients with thyroid cancer).

conclusionTT and male sex were independent risk factors for LOS but were not associated with a higher risk of RLNP in this series. When LOS occurs during a planned TT, the surgeon should consider the risk of true RLN injury and the nature of thyroid disease justifying the removal of the contralateral lobe.

Indexed as

Intraoperative ComplicationsMonitoring, IntraoperativePostoperative ComplicationsRecurrent Laryngeal Nerve InjuriesThyroidectomyThyroid NeoplasmsVocal Cord ParalysisAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRetrospective StudiesIntraoperative neuromonitoringLoss of signalRecurrent laryngeal nerveSurgeryThyroidectomy

Identifiers

PMID41162991
PMCPMC12573864

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.