ReviewBMC musculoskeletal disorders2025
Hinged total knee arthroplasty in two female patients with type 1 diabetes-associated charcot neuroarthropathy: case reports and a review of the literature series.
Review in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCharcot neuroarthropathy (CN) is a rare musculoskeletal disorder caused by peripheral neuropathy, predominantly affecting the forefoot and ankle joints in diabetic patients. While more common in type 2 diabetes, type 1 diabetes-associated CN carries high risks of disability and mortality due to delayed diagnosis and nonspecific pathophysiology. Knee joint CN in type 1 diabetes remains exceptionally rare, with limited reports on standardized management-particularly regarding knee arthroplasty outcomes. CASE PRESENTATION: We report two female type 1 diabetes patients with knee joint CN. Both presented with poorly controlled hyperglycemia (blood glucose > 20 mmol/L) and elevated HbA1c. Each underwent total knee arthroplasty (TKA); one patient additionally received autologous bone grafting with titanium mesh screw fixation for severe bone defects, Intraoperative pathological examination was performed in all cases to rule out infection.
conclusionThese cases highlight the complexity of managing knee CN in type 1 diabetes. TKA represents a viable intervention, though outcomes may vary based on surgical adjuncts like bone grafting. This report, contextualized with a literature review, underscores the need for individualized approaches in this high-risk population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.