Evidence map›Paper›PMID 41162938›Full record

ArticleBMC women's health2025

Sexual activity and functioning after breast cancer treatment: perspectives on the importance of pleasure from a radiotherapy cohort.

Melanie Besculides, Lauren Carney, Ksenia Gorbenko, Sheryl Green, Melissa Brito, Jezelle Lynch, Carly Feldman, Cindy Munoz, Madhu Mazumdar, Deborah C Marshall

Abstract read
In one paragraph

Article in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Melanie BesculidesInstitute for Healthcare Delivery Science, Mount Sinai Health System, New York, NY, USA. Melanie.besculides@mountsinai.org.
Lauren CarneyDepartment of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Ksenia GorbenkoInstitute for Healthcare Delivery Science, Mount Sinai Health System, New York, NY, USA.
Sheryl GreenDepartment of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Melissa BritoDepartment of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jezelle LynchDepartment of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Carly FeldmanSidney Kimmel Medical College, Philadelphia, PA, USA.
Cindy MunozDepartment of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Madhu MazumdarInstitute for Healthcare Delivery Science, Mount Sinai Health System, New York, NY, USA.
Deborah C MarshallDepartment of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Funding

Training Program in Cancer Prevention and Control for Priority PopulationsT32CA225617 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Guy H Montgomery, JUAN P WISNIVESKY · 2018 to 2026
$2.6M
National Institutes of Health (Office of the Director) DP5OD031876NCI NIH HHS T32CA225617
6 · The paper itself

Abstract

backgroundBreast cancer affects millions of women and while treatment can be lifesaving, it also has numerous side effects, including those related to sexual function, which often impact the ability to experience pleasure from sex. This study aimed to understand how breast cancer survivors define sexual activity, identify important aspects, and ascertain perceived impacts of treatment on sexual activity and function, particularly related to pleasure.

methodsSemi-structured interviews were conducted with women who were breast cancer survivors at least one-year post-radiation. Priority populations were oversampled (racial/ethnic/sexual/gender minorities, those aged over 65 or under 45). The sample included 23 participants: 11 Non-Hispanic White, 8 Non-Hispanic Black, 2 Non-Hispanic Asian, 2 Hispanic/Latinx, and 1 transgender participant. Mean age was 58.6 years (range 34-77, SD = 12.2).

resultsFour themes were identified: 1) Sexual activity is defined broadly, and intimacy and pleasure are key. Participants defined sex in broad terms and highlighted the importance of being close with partners and pleasure. Sex was important across the lifespan and among participants from different backgrounds, 2) Few anticipated sexual side effects: Although treatment side effects were common, few expected them, 3) Clinician communication is lacking or mistimed: Participants did not remember conversations about potential side effects because they did not happen, or they were not in a mental space to process them, 4) Sexual health side effects are plentiful and for many, long-lasting. Changes to breast sensitivity and ability to achieve orgasm were reported. Breast cancer survivors conceptualized sexual activity through a broad lens and highlighted the importance of sex, particularly pleasure and intimacy. Participants reported a variety of negative effects from treatment that impacted pleasure, and patient/clinician communication on sexual health was perceived to be lacking.

conclusionClinicians may improve survivors' quality of life by acknowledging clinical origins of sexual dysfunction, prioritizing pleasure and intimacy in the development of interventions to prevent or mitigate sexual side effects and fostering open communication.

Indexed as

Breast NeoplasmsCancer SurvivorsPleasureSexual BehaviorAdultAgedCohort StudiesFemaleHumansMiddle AgedQualitative ResearchQuality of LifeRadiotherapyBreast cancerPleasureQuality of lifeRadiotherapySexual health

Identifiers

PMID41162938
PMCPMC12570742

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.