ArticleBMC infectious diseases2025
Poor glycemic control among people with diabetes mellitus is associated with tuberculosis infection: a cross-sectional study in Nepal.
Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetes mellitus (DM) raises the risk of contracting Tuberculosis (TB) infection and progressing to TB disease. Screening people with diabetes for TB infection and offering preventive treatment can, therefore, minimize the likelihood of progression to TB disease. This study aimed to test if glycemic control among patients with diabetes mellitus presenting to a tertiary care teaching hospital in Nepal is associated with tuberculosis infection.
methodsThis cross-sectional study was conducted among patients aged ≥ 18 years, with a self-reported diabetes mellitus or HbA1C value of ≥ 6.5%, at a tertiary facility in Kathmandu, Nepal. Participants underwent Chest X-rays and TB symptoms screening for TB disease. TB infection status was identified in those without TB disease by an induration of ≥ 10 mm in the Tuberculin Skin Test (TST). Clinical, social, anthropometric, and vaccination information were abstracted. Multiple logistic regression models were used.
resultsPulmonary TB disease was found in 19 of the 473 patients screened (4.0%) of whom 18 were bacteriologically confirmed. Of the 422 patients analysed, the median age was 54.5 (IQR 47-64.7) years, 316 (74.9%) had poor glycemic control and 193 patients had positive TST (TB infection prevalence - 45.7%). Individuals with poor glycemic control had more than three times the odds of testing TST-positive compared to those with good glycemic control (OR 3.30 [95% CI: 1.78-6.44]), after adjusting for relevant covariates.
conclusionsTB infection and disease prevalence remain high in people with diabetes mellitus even with bidirectional screening policies and widespread metformin use. Individuals with poorly controlled diabetes mellitus could be a priority group for targeted TB infection testing and preventive treatment. CLINICAL TRIAL NUMBER: Not applicable.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.