ArticleBMC cardiovascular disorders2025
Before the diagnosis: quality of life in patients presenting with chest pain undergoing Bruce protocol stress testing.
Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundA stress test is commonly used as an initial evaluation tool for determining a possible cardiac origin for chest pain. This study was performed to test the hypothesis that patients with a positive stress test will have a significantly lower health-related quality of life (HRQoL) than patients with a negative stress test.
methodsThis study was a two-group non-experimental design where group assignment was based on the result of the stress test. Participants completed an HRQoL questionnaire (EuroQol-5D) prior to performing the Bruce treadmill stress test. The stress test was considered positive if participants reported chest pain or developed electrocardiogram ST-T changes or arrhythmia during the test.
resultsA total of 123 participants completed the study with 33 participants with a positive stress test and 90 participants with a negative stress test. Participants with a negative stress test reported a significantly lower (p = 0.014) HRQoL as compared to participants with a positive stress test. In the overall sample, current smokers (p < 0.001) and women (p = 0.02) were found to have a lower HRQoL.
conclusionsPatients with non-cardiac chest pain can experience lower HRQoL. The HRQoL was not related to results of the diagnostic testing. This study underscores that patients with non-cardiac chest pain could benefit from additional psychological assessment and treatment.
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