Evidence map›Paper›PMID 41162862›Full record

SynthesisBMC infectious diseases2025

Dermatological manifestation of HIV infection: systematic review and meta-analysis.

Muhammad Anshory, Raden Mohamad Rendy Ariezal Effendi, Milanitalia Gadys Rosandy, Handono Kalim, Tamar E C Nijsten, Renske Schappin, Jan L Nouwen, Hok Bing Thio

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Relationship Between Onychomycosis and HIV: A Systematic Review.Journal of fungi (Basel, Switzerland) · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Muhammad AnshoryDepartment of Dermatology, Erasmus University Medical Centre (Erasmus MC), Dr. Molewaterplein 40, Rotterdam, 3015 GD, The Netherlands.
Raden Mohamad Rendy Ariezal EffendiDepartment of Dermatology, Erasmus University Medical Centre (Erasmus MC), Dr. Molewaterplein 40, Rotterdam, 3015 GD, The Netherlands.
Milanitalia Gadys RosandyDepartment of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, 65145, Indonesia.
Handono KalimDepartment of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, 65145, Indonesia.
Tamar E C NijstenDepartment of Dermatology, Erasmus University Medical Centre (Erasmus MC), Dr. Molewaterplein 40, Rotterdam, 3015 GD, The Netherlands.
Renske SchappinDepartment of Dermatology, Erasmus University Medical Centre (Erasmus MC), Dr. Molewaterplein 40, Rotterdam, 3015 GD, The Netherlands.
Jan L NouwenDepartment of Medical Microbiology and Infectious Diseases, Erasmus University Medical Centre (Erasmus MC), Rotterdam, 3015 GD, The Netherlands.
Hok Bing ThioDepartment of Dermatology, Erasmus University Medical Centre (Erasmus MC), Dr. Molewaterplein 40, Rotterdam, 3015 GD, The Netherlands. h.thio@erasmusmc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSince its discovery in 1981, AIDS has become a significant global public health issue, impacting more than 38 million people worldwide with HIV. Despite a 32% reduction in new HIV infections since 2010, millions continue to be affected, often experiencing dermatological problems. This study aims to examine the epidemiology of these dermatological issues in HIV patients by reviewing existing research.

methodsWe conducted an extensive search across MEDLINE, Web of Science, Google Scholar, and grey literature, encompassing all languages and publications from 1975 to November 30, 2022. Various study designs were considered. To assess article quality, we used a risk bias instrument by JBI, performed meta-analysis and regression analysis to explore relationships between dermatological manifestations and factors such as age and region. Articles underwent double-blind review, with discrepancies resolved by a third reviewer to ensure precision and consistency.

resultsThe analysis of 145 articles involving 41,285 HIV patients identified approximately 28,448 cases of patients with dermatological diseases. Most patients had a single dermatological disease, and the majority were male adults. Research was concentrated in South Asia, North America, Western Europe, and West Africa. The most prevalent dermatological issues among 60,064 events were oral candidiasis (8.88%), dermatophytosis, seborrheic dermatitis, warts, and herpes zoster. The meta-analysis revealed an overall prevalence of 76% (95% CI: 72% - 81%) with significant heterogeneity (I

conclusionsThis study highlights the high prevalence of dermatological diseases in HIV patients, especially oral candidiasis, dermatophytosis, and seborrheic dermatitis, with a focus on male adults as the most affected demographic group.

Indexed as

HIV InfectionsSkin DiseasesAdultCandidiasis, OralDermatitis, SeborrheicFemaleHumansMalePrevalenceAIDSDermatological diseaseDermatological manifestationEpidemiologyHIVSkin

Identifiers

PMID41162862
PMCPMC12573998

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.