Evidence map›Paper›PMID 41162667›Full record

ReviewArchives of gynecology and obstetrics2025

The molecular pathogenesis of placenta accreta spectrum disorder and its clinical applications.

Min Zhao, Lizhou Sun, Dan Wu

Abstract readReview
In one paragraph

Review in Archives of gynecology and obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Min ZhaoDepartment of Obstetrics and Gynecology, Women's Hospital of Nanjing Medical University, Nanjing Women and Children's Healthcare Hospital, 123 Tianfeixiang, Mochou Road, Qinhuai District, Nanjing, 210004, China.ORCID 0000-0002-9888-4443
Lizhou SunDepartment of Obstetricsand Gynecology, First Affiliated Hospital of NanjingMedical University, Nanjing, 210029, JiangSu Province, China.
Dan WuDepartment of Obstetrics and Gynecology, Women's Hospital of Nanjing Medical University, Nanjing Women and Children's Healthcare Hospital, 123 Tianfeixiang, Mochou Road, Qinhuai District, Nanjing, 210004, China. wudanfc@njmu.edu.cn.ORCID 0000-0002-5190-1277

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Placenta accreta spectrum (PAS) is a serious obstetric complication, characterized by the placenta accreta and increta to the uterine wall, which fails to detach spontaneously from the uterine following childbirth, potentially resulting in severe hemorrhage and additional complications. The incidence of PAS is increasing in the world, which is mainly attributed to a global escalation in cesarean section rates, underscoring the critical need to elucidate its molecular pathogenesis and to devise efficacious clinical interventions. Recent studies have identified novel molecular mechanisms that have significantly enhanced our comprehension of disease pathophysiology and informed predictive and therapeutic strategies. Here, we review the principal molecular pathogenesis of PAS, explore the potential translation of these findings into clinical applications, and assess the impact of emerging technologies on advancing research in this domain.

Indexed as

Placenta AccretaCesarean SectionFemaleHumansPregnancyAngiogenesisBiomarkersMolecular pathogenesisPlacenta accreta spectrum

Identifiers

PMID41162667
PMCPMC12705845

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.