Evidence map›Paper›PMID 41162666›Full record

ArticleArchives of gynecology and obstetrics2025

The risk of infertility and dietary inflammatory index, a case-control study in Iran.

Roya KabodMehri, Farhad Vahid, Sheyda Nami, Hadis Ghadimi, Masoumeh Dorosti, Faezeh Tejareh, Ali Shamsi-Goushki, Parsa Bahmani, Hoora Karimi, Marjan Ajami and 2 more

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In one paragraph

Article in Archives of gynecology and obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Roya KabodMehriReproductive Health Research Center, Department of Obstetrics and Gynecology, School of Medicine, Al-Zahra Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Farhad VahidNutrition and Health Group, Department of Precision Health, Luxembourg Institute of Health,, Strassen, Luxembourg.
Sheyda NamiDepartment of clinical Biochemistry, Iran University of Medical Sciences, Tehran, Iran.
Hadis GhadimiReproductive Health Research Center, Department of Obstetrics and Gynecology, School of Medicine, Al-Zahra Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Masoumeh DorostiStudent Research Committee, Department of Nutrition, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Faezeh TejarehDepartment of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Ali Shamsi-GoushkiDepartment of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Parsa BahmaniDepartment of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hoora KarimiReproductive Health Research Center, Department of Obstetrics and Gynecology, School of Medicine, Al-Zahra Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Marjan AjamiDepartment of Food and Nutrition Policy and Planning, School of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran. marjan.ajami80@gmail.com.
Saeid DoaeiDepartment of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Doaei@gums.ac.ir.
Maryam GholamalizadehUnit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfertility is defined as the inability to conceive after 12 months of unprotected sexual intercourse and affects 15% of couples globally. Diet influences inflammatory factors, potentially affecting ovarian reserve and thus may have a role in infertility. The present study aimed to assess the association between infertility and the Dietary Inflammatory Index (DII).

methodsThis case-control study was conducted at Al-Zahra Hospital, Rasht, Iran, on 123 infertile women and 123 healthy participants. Food intake was assessed using a validated FFQ. The DII was calculated, and logistic regression analysis was performed to assess the relationship between DII and ovarian reserve.

resultsIndividuals with a higher DII had a greater risk of infertility compared to those with a lower DII (OR = 2.08, CI 95% = 1.024-4.248, P = 0.043) after adjustment for age, weight, body mass index, intake of anti-inflammatory supplements, suffering from underlying disease, smoking, alcohol consumption, and physical activity. Further adjustments for infertility duration, thyroid disorders, FSH, LH, and number of fertilities did not change the results.

conclusionThe dietary inflammatory index (DII) was positively associated with infertility. A higher inflammatory diet may increase the likelihood of infertility. Further research is needed to fully understand this connection.

Indexed as

DietInfertility, FemaleInflammationAdultCase-Control StudiesFemaleHumansIranLogistic ModelsOvarian ReserveRisk FactorsYoung AdultDietDietary inflammatory indexDIIInfertility

Identifiers

PMID41162666
PMCPMC12705718

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.