Evidence map›Paper›PMID 41162644›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2025

Long-term outcome in 415 operated cases with single suture scaphocephaly.

Sofie Dietvorst, Lawrence Choi, Aitor de Gea Rico, Anusha Hennedige, Christian Duncan, Vejay Vakharia, Chris Parks, Ajay Sinha

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Postoperative raised ICP after minimally invasive surgery for monosutural craniosynostosis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Pooled it
  2. Neuro-developmental outcome in sagittal synostosis; Analysis of 488 children in the context of the existing literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Review
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sofie DietvorstDepartment of Neurosurgery, Alder Hey Children's Hospital, Liverpool, UK. sofie.dietvorst@alderhey.nhs.uk.
Lawrence ChoiDepartment of Neurosurgery, Auckland City Hospital, Auckland, New Zealand.
Aitor de Gea RicoCraniofacial Unit, Alder Hey Children's Hospital, Liverpool, UK.
Anusha HennedigeCraniofacial Unit, Alder Hey Children's Hospital, Liverpool, UK.
Christian DuncanDepartment of Maxillofacial Surgery, Alder Hey Children's Hospital, Liverpool, UK.
Vejay VakhariaDepartment of Neurosurgery, Alder Hey Children's Hospital, Liverpool, UK.
Chris ParksDepartment of Neurosurgery, Alder Hey Children's Hospital, Liverpool, UK.
Ajay SinhaDepartment of Neurosurgery, Alder Hey Children's Hospital, Liverpool, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere are multiple options available for the surgical management of non-syndromic scaphocephaly. The goals of surgery are to correct the cranial deformity in order to optimize overall cosmetic appearance and to prevent raised intracranial pressure (ICP). At Alder Hey Children's Hospital NHS Trust, we offer a range of surgical procedures for single-suture scaphocephaly (SSS) from endoscopic strip craniectomy (ESC) with helmet therapy, sagittal suturectomy, and barrel staving - known as passive vault remodeling (PassiveVR), to an active subtotal (SVR) or total vault remodeling (TVR).

methodsWe conducted a retrospective analysis of all operated scaphocephaly patients at Alder Hey. All consecutive patients from 2012 to 2023 were included. Syndromic or multisuture synostosis cases were excluded. Age, type of surgery, issues of ICP at diagnosis, cephalic index (CI) pre- and postoperative, type and indication for reoperation, and length of follow-up were gathered in the database.

resultsFour hundred fifteen patients were included; 200 underwent PassiveVR, 206 underwent SVR/TVR, 8 underwent ESC + helmet, and one was treated with springs. The median follow-up period was 46 months. Eighteen patients underwent treatment due to high ICP related to synostosis, with the median age at surgery being 54 months in this group. Reoperations for intracranial hypertension or persistent abnormal shape were done for 17 patients treated initially with PassiveVR (8.5%), for 4 patients initially treated with SVR/TVR (1.9%), and for 1 patient initially treated with ESC + helmet (12.5%). Postoperative CI was significantly higher than preoperative CI in all operated patients (paired t-testing, p < 0.01).

conclusionPassiveVR and SVR/TVR are the most common procedures in our centre to treat scaphocephaly, with PassiveVR being performed earlier in life. In less than 10% of PassiveVR cases, reoperation due to increased ICP or abnormal head shape is required, with the benefit of PassiveVR being less invasive than SVR/TVR. Our experience with ESC is limited at present, but preliminary findings from this study suggest the need for long-term follow-up in order to identify early evidence of raised ICP or persistent deformity in this patient subgroup.

Indexed as

Cranial SuturesCraniosynostosesCraniotomyPlastic Surgery ProceduresChildChild, PreschoolFemaleFollow-Up StudiesHumansInfantMaleRetrospective StudiesTreatment OutcomeCephalic indexEndoscopic suturectomyIntracranial pressurePassive vault remodelingScaphocephalyTotal vault remodeling

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.