Evidence map›Paper›PMID 41162638›Full record

ReviewLa Radiologia medica2026

Recommendations for the diagnosis and treatment of spontaneous intracranial hypotension.

Elisa Francesca Maria Ciceri, Luigi Cirillo, Francesco Causin, Ferdinando Caranci, Alessandra Splendiani, Mario Muto, Mauro Bergui

Abstract readReview
In one paragraph

Review in La Radiologia medica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elisa Francesca Maria CiceriUOC Radiologia Diagnostica E Neuroradiologia Interventistica, Istituto Neurologico C. Besta, Milan, Italy.
Luigi CirilloUO Neuroradiologia, IRCCS Istituto Delle Scienze Neurologiche Di Bologna, Bologna, Italy. luigi.cirillo2@unibo.it.ORCID http://orcid.org/0000-0002-0424-3400
Francesco CausinAOPD UOC Neuroradiologia, Azienda Ospedale Università Di Padova, Padua, Italy.
Ferdinando CaranciDipartimento Di Medicina Di Precisione, Università Degli Studi Della Campania "Luigi Vanvitelli", Naples, Italy.
Alessandra SplendianiDipartimento Di Scienze Cliniche Applicate E Biotecnologiche, Università Degli Studi Dell'Aquila, L'Aquila, Italy.
Mario MutoDiagnostic and Interventional Neuroradiology Unit, Cardarelli Hospital, Naples, Italy.
Mauro BerguiDepartment of Neuroscience, Neuroradiological Unit, University of Turin; Azienda Ospedaliera Città Della Salute E Della Scienza Hospital, Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous intracranial hypotension (SIH) is a syndrome characterized by disabling orthostatic headache, resulting from a reduction in volume of cerebrospinal fluid (CSF) likely caused by a CSF leak. It mainly affects women at working age and is probably underdiagnosed. This protocol aims to present a proposal for a practical approach to the diagnosis and treatment of SIH. After a descriptive section of the clinical manifestations of SIH, we present a step-by-step model of action to confirm its diagnosis and treatment, considering different clinical scenarios. The aim is, therefore, to facilitate clinical decision-making through a systematized and individualized approach, aiming to best interest of the patient.

Indexed as

Intracranial HypotensionFemaleHumansCSF leakCSF-venous fistulaImaging diagnosisSpontaneous intracranial hypotension

Identifiers

PMID41162638
PMCPMC12932351

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.