Evidence map›Paper›PMID 41162501›Full record

Trial reportScientific reports2025

Laryngeal mask airway improves hemodynamics and reduces pharyngeal discomfort in total joint arthroplasty.

Wenyu Jiang, Xue Jiang, Yujuan Liu, Hong Xu, Yucan Ju, Yawen Xiao, Jinwei Xie, Qiang Huang, Ren Liao, Fuxing Pei

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wenyu JiangDepartment of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, No. 37, Guoxue Road, Wuhou District, Chengdu, 610041, Sichuan, People's Republic of China.
Xue JiangDepartment of Anesthesia and Operation Center, Research Unit for Perioperative Stress Assessment and Clinical Decision, Chinese Academy of Medical Sciences (2018RU012), West China Hospital of Sichuan University, No. 37, Guoxue Road, Wuhou District, Chengdu, 610041, Sichuan, People's Republic of China.
Yujuan LiuDepartment of Anesthesia and Operation Center, Research Unit for Perioperative Stress Assessment and Clinical Decision, Chinese Academy of Medical Sciences (2018RU012), West China Hospital of Sichuan University, No. 37, Guoxue Road, Wuhou District, Chengdu, 610041, Sichuan, People's Republic of China.
Hong XuDepartment of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, No. 37, Guoxue Road, Wuhou District, Chengdu, 610041, Sichuan, People's Republic of China.
Yucan JuDepartment of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, No. 37, Guoxue Road, Wuhou District, Chengdu, 610041, Sichuan, People's Republic of China.
Yawen XiaoOperating Room, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, No. 37, Guoxue Road, Wuhou District, Chengdu, 610041, Sichuan, People's Republic of China.
Jinwei XieDepartment of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, No. 37, Guoxue Road, Wuhou District, Chengdu, 610041, Sichuan, People's Republic of China.
Qiang HuangDepartment of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, No. 37, Guoxue Road, Wuhou District, Chengdu, 610041, Sichuan, People's Republic of China. huangqiang4325@126.com.
Ren LiaoDepartment of Anesthesia and Operation Center, Research Unit for Perioperative Stress Assessment and Clinical Decision, Chinese Academy of Medical Sciences (2018RU012), West China Hospital of Sichuan University, No. 37, Guoxue Road, Wuhou District, Chengdu, 610041, Sichuan, People's Republic of China. liaoren7733@wchscu.cn.
Fuxing PeiDepartment of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, No. 37, Guoxue Road, Wuhou District, Chengdu, 610041, Sichuan, People's Republic of China.

Funding

1·3·5 project for disciplines of excellence-Clinical Research Fund, West China Hospital, Sichuan University 2023HXFH013the National Natural Science Foundation of China 82402773the Postdoctoral Fellowship Program of CPSF under Grant Number GZC20231825
6 · The paper itself

Abstract

Endotracheal intubation (EI) can adversely affect hemodynamics and patient satisfaction. Concerns regarding the safety of the laryngeal mask airway (LMA) in total joint arthroplasty (TJA) arise from patient positioning and the surgical procedure. This study aimed to compare the effects of EI and LMA on hemodynamics and postoperative pharyngeal discomfort in TJA, and evaluate LMA's safety. In this prospective trial, 100 patients undergoing TJA due to end-stage joint disease at our medical center between August 2023 and August 2024 were enrolled. Following the induction of anesthesia, patients were randomly assigned to either EI or LMA. Postoperative sore throat and hoarseness were assessed upon awakening and at 6, 24, and 48 h. The primary outcome was postoperative pharyngeal discomfort; secondary outcomes were hemodynamic stability and airway complications. At 6 h post-TJA, sore throat (32% vs 12%, P = 0.030) and hoarseness (70% vs 36%, P = 0.003) were significantly lower in the LMA group. At 24 h, hoarseness remained lower (22% vs 6%; P = 0.021). The incidence of hemodynamic instability during airway establishment (40% vs 4%, P < 0.001), removal (78% vs 24%, P < 0.001), and during TJA (62% vs 14%, P < 0.001) was significantly lower in the LMA group. No significant differences in airway complications were found. LMA use in TJA reduced postoperative pharyngeal discomfort and improved hemodynamic stability, making it a safe and effective alternative to EI. Trial registration: The Chinese Clinical Trial Registry (14/08/2023, ChiCTR2300074701).

Indexed as

Arthroplasty, ReplacementHemodynamicsIntubation, IntratrachealLaryngeal MasksPharyngitisAgedFemaleHoarsenessHumansMaleMiddle AgedPharynxPostoperative ComplicationsProspective StudiesEndotracheal intubationHemodynamicsLaryngeal mask airwayPharyngeal discomfortTotal joint arthroplasty

Identifiers

PMID41162501
PMCPMC12572176

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.