Evidence map›Paper›PMID 41162131›Full record

ArticleThe Lancet. Public health2025

Unsecured debt in early adulthood and premature mortality in adults in the USA: a longitudinal analysis of prospective national cohort data.

Samuel L Swift, Zihan Chen, Calvin Colvin, Katrina Kezios, Sebastian Calonico, Adina Zeki Al Hazzouri

Abstract read
In one paragraph

Article in The Lancet. Public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Samuel L SwiftCollege of Population Health, University of New Mexico, Health Sciences Center, Albuquerque, NM, USA.
Zihan ChenDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Calvin ColvinDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Katrina KeziosDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
Sebastian CalonicoGraduate School of Management, University of California in Davis, Davis, CA, USA.
Adina Zeki Al HazzouriDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA. Electronic address: az2567@columbia.edu.

Funding

Building an unbiased pooled cohort for the study of lifecourse social and vascular determinants of Alzheimer's Disease and Related DisordersR01AG072681 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GLYMOUR, MEDELLENA MARIA, ZEKI AL HAZZOURI, ADINA · 2021 to 2025
$4.0M
Investigating financial wellbeing, biological aging, and risk of Alzheimers disease and related dementias in a life course synthetic cohortR00AG084769 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Katrina L Kezios · 2025 to 2026
$489k
Investigating financial wellbeing, biological aging, and risk of Alzheimers disease and related dementias in a life course synthetic cohortK99AG084769 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KEZIOS, KATRINA L · 2024 to 2025
$263k
NIA NIH HHS K99 AG084769NIA NIH HHS R00 AG084769NIA NIH HHS R01 AG072681
6 · The paper itself

Abstract

backgroundPremature mortality rates are higher in the USA than other peer nations. Few studies have assessed the association between cumulative unsecured debt and subsequent premature mortality. The aim of this study was to investigate the association between cumulatively accrued unsecured debt over 20 years of early adulthood and subsequent premature mortality in midlife (age 41-62 years).

methodsFor this longitudinal analysis, we used data from 6954 participants included in the US National Longitudinal Survey of Youth 1979. Participants were followed up from 1985 to 2004 to assess debt trajectory, and from 2004 to 2018 to assess premature mortality. A group-based trajectory model was used to classify four groups of unsecured debt trajectories: no debt, constant low debt, constant medium debt, and increasing debt. Multivariable adjusted Cox proportional hazards models were used to assess associations between debt trajectory and mortality.

findingsOf the 6954 participants included in our analysis, 5670 (81·5%) individuals had constant low debt, 712 (10·2 %) had constant medium debt, 148 (2·1%) had increasing debt, and 424 (6·1%) had no debt. In adjusted models, the risk of mortality was 89% higher in the increasing debt group than the constant low debt group (hazard ratio 1·89 [95% CI 1·14-3·12]). In unadjusted models, individuals with no debt had a numerically higher risk of premature mortality compared with those with constant low debt; however, this difference was not statistically significant.

interpretationCumulative increasing unsecured debt in early adulthood was associated with increased risk of premature mortality in midlife. Interventions and policies targeting unsecured debt might reduce premature mortality.

fundingNational Institute of Health National Institute on Aging.

Indexed as

Mortality, PrematureAdultFemaleHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesSocioeconomic FactorsUnited States

Identifiers

PMID41162131
PMCPMC12700172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.