← GLP-1 receptor agonists × body weight & composition

SynthesisThe Cochrane database of systematic reviews2025

Liraglutide for adults living with obesity.

Nicolás Meza et al.PubMed ↗Full text ↗Publisher ↗

  • Liraglutidelooks good hereLower percentage weight change.Randomised, large.

What the trial testedrandomised · 9,937 people · 2025

Randomised vs placebo

Lowered percentage weight change

−4.72−5.32 to −4.12

liraglutide vs placebo

As reported

difference −4.72, 95% CI −5.32 to −4.12 · the paper's word: percentage weight change from baseline

Who was studied, and how

9,937people with obesity, in this paper

The trial randomly assignedassigned by chance

liraglutide
placebo

Lowered percentage weight change−4.72

randomised

the abstract, start to end

… from baseline (mean difference (MD) -4.72, 95% confidence interval (CI) …

← favours treatmentfavours comparator →
could be chance
Percentage weight change from baselineliraglutide vs placebo
−4.72−5.32 to −4.12
GLP-1 receptor agonistsBody weight & composition

GLP-1 receptor agonists × body weight & compositionhelps?replicated

unlikelylikely
0.91not counted
← favours treatmentfavours comparator →
more certainless certain
1 / 6

2 papers cite it

2025
2026
this papercites it
Full record →Abstract, authors, funding and every citing paper · PMID 41161684