Evidence map›Paper›PMID 41161337›Full record

ArticleOnline journal of public health informatics2025

Evidence-Based Mental Health at Scale: Benchmarking Retrospective Cohort Study of a Digital Employee Benefits Program for Depression and Anxiety.

Emily J Ward, Matt Hawrilenko, Millard Brown, Adam M Chekroud

Abstract read
In one paragraph

Article in Online journal of public health informatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emily J WardSpring Health, New York, NY, United States.ORCID https://orcid.org/0000-0002-2789-2753
Matt HawrilenkoSpring Health, New York, NY, United States.ORCID https://orcid.org/0000-0001-9556-4391
Millard BrownSpring Health, New York, NY, United States.ORCID https://orcid.org/0000-0003-2225-9243
Adam M ChekroudSpring Health, New York, NY, United States.ORCID https://orcid.org/0000-0002-0497-596X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDepression and anxiety affect millions worldwide; yet, many people face barriers to timely and effective mental health care, underscoring the need for scalable, high-quality interventions.

objectiveThis study aimed to evaluate the clinical effectiveness and quality of a centralized, employer-sponsored mental health program in treating depression and anxiety during a period of rapid growth in access to mental health care.

methodsThis retrospective cohort study included participants using a digital mental health benefit (Spring Health), sponsored by 589 US employers from 2021 to 2024. Participants had access to therapists, psychiatrists, and care navigators. Primary measures were clinical effectiveness (treatment duration, Patient Health Questionnaire 9-item depression scale, Generalized Anxiety Disorder 7-item Scale) and clinical outcomes (reliable change, recovery, and remission). Outcomes were benchmarked to meta-analytic results of evidence-based therapy.

resultsA total of 52,929 adult participants started therapy from among 6868 providers during the study period, scored positive for depression or anxiety, and had at least one mental health assessment before and during treatment. Depression symptoms decreased with each log-day in treatment, resulting in a total reduction of 6.91 (95% CI -6.84 to -6.98) points at one-week post treatment, corresponding to a large effect size (d=1.61; 95% CI 1.60-1.63), significantly greater than the meta-analytic pre-post benchmark for psychotherapy (effect size difference=0.13, z=15.6, P<.001). Anxiety symptoms also decreased, resulting in a total reduction of 6.01 points (95% CI -5.95 to -6.08), corresponding to a large effect size (d=1.82; 95% CI 1.80 to 1.84), significantly greater than the meta-analytic benchmarks (effect size difference=0.64, z=61.9, P<.001). White participants and participants of color had similar outcomes. Logistic regression showed 92.3% (95% CI 92.0% to 92.5%) of participants' symptoms (in depression or anxiety) reliably improved, and 61.7% (95% CI 61.1% to 62.4%) achieved remission by 1-week posttreatment.

conclusionsAmong a large and diverse sample, using a digital mental health benefit with a centralized system of care produces clinical outcomes in depression and anxiety significantly greater than what is typically observed through meta-analyses of psychotherapy. By using data to monitor, incentivize, and improve quality of care, the clinical outcomes outperform or equal benchmarks as a growing number of individuals across race, gender, and age access mental health care.

Indexed as

clinical outcome evaluationdepression and anxietydigital mental health benefitemployer-sponsored mental healthmeasurement-based care

Identifiers

PMID41161337
PMCPMC12612640

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.