Evidence map›Paper›PMID 41160982›Full record

ArticleJournal of biophotonics2026

Systemic Effects of Vascular Photobiomodulation on Early Macrophage Recruitment During Skeletal Muscle Repair.

Raquel Lira Ortiz da Silva, Tainá Caroline Dos Santos Malavazzi, Aline Souza Silva, Sandra Kalil Bussadori, Anna Carolina Ratto Tempestini Horliana, Fabio Daumas Nunes, Kristianne Porta Santos Fernandes, Maria Fernanda Setubal Destro Rodrigues, Raquel Agnelli Mesquita-Ferrari

Abstract read
In one paragraph

Article in Journal of biophotonics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Raquel Lira Ortiz da SilvaPostgraduate Program in Biophotonics Medicine, Universidade Nove de Julho (UNINOVE), Sao Paulo, Sao Paulo, Brazil.ORCID 0009-0004-3320-9772
Tainá Caroline Dos Santos MalavazziDepartment of Oral Pathology, School of Dentistry, University of São Paulo (FOUSP), São Paulo, Sao Paulo, Brazil.ORCID 0000-0002-2770-2753
Aline Souza SilvaPostgraduate Program in Biophotonics Medicine, Universidade Nove de Julho (UNINOVE), Sao Paulo, Sao Paulo, Brazil.ORCID 0009-0000-6372-4506
Sandra Kalil BussadoriPostgraduate Program in Biophotonics Medicine, Universidade Nove de Julho (UNINOVE), Sao Paulo, Sao Paulo, Brazil.ORCID 0000-0002-9853-1138
Anna Carolina Ratto Tempestini HorlianaPostgraduate Program in Biophotonics Medicine, Universidade Nove de Julho (UNINOVE), Sao Paulo, Sao Paulo, Brazil.ORCID 0000-0003-3476-9064
Fabio Daumas NunesDepartment of Oral Pathology, School of Dentistry, University of São Paulo (FOUSP), São Paulo, Sao Paulo, Brazil.ORCID 0000-0002-7785-6785
Kristianne Porta Santos FernandesPostgraduate Program in Biophotonics Medicine, Universidade Nove de Julho (UNINOVE), Sao Paulo, Sao Paulo, Brazil.ORCID 0000-0001-7156-9286
Maria Fernanda Setubal Destro RodriguesPostgraduate Program in Biophotonics Medicine, Universidade Nove de Julho (UNINOVE), Sao Paulo, Sao Paulo, Brazil.ORCID 0000-0002-3067-9224
Raquel Agnelli Mesquita-FerrariPostgraduate Program in Biophotonics Medicine, Universidade Nove de Julho (UNINOVE), Sao Paulo, Sao Paulo, Brazil.ORCID 0000-0001-5142-9526

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 302771/2025-5Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.836078/2023-00Fundação de Amparo à Pesquisa do Estado de São Paulo [2020/13976-0] and [2023/04948-0]UNINOVE
6 · The paper itself

Abstract

Muscle injuries involve a complex inflammatory response in which macrophages are essential for proper tissue repair. Dysregulation of this process can impair regeneration. This study investigated the effects of vascular photobiomodulation (VPBM), a non-invasive therapy applied via the caudal vein/artery, on macrophage dynamics in acute skeletal muscle injury. Wistar rats were divided into Control, Injury, Pre-VPBM+Injury, and Injury+Post-VPBM groups. VPBM (780 nm, 40 mW, 3.2 J) was applied preventively or therapeutically. Animals were euthanized on days 1, 2, 5, and 7 post-injury for CD68

Indexed as

Blood VesselsLow-Level Light TherapyMacrophagesMuscle, SkeletalRegenerationWound HealingAnimalsAntigens, CDMaleMannose ReceptorRatsRats, WistarAntigens, CDMannose Receptorcryoinjurylow‐level laser therapymacrophagesmuscle repairvascular photobiomodulation

Identifiers

PMID41160982
PMCPMC12872372

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.