ArticleMolecular pharmaceutics2025
Comparison of In-Vitro and In-Vivo Drug Release of Dexamethasone/PLGA Intravitreal Implants Using Two In-Vitro Release Methods and a Rabbit Model.
Coleman Johnson, Esther Maier, Aanya Bhalla, Eric Crowell, Yan Wang, Bin Qin, Feng Zhang
Abstract readComparative Study
In one paragraphArticle in Molecular pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors.
Coleman JohnsonDivision of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0009-0007-1886-6143 Esther MaierDivision of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas at Austin, Austin, Texas 78712, United States.
Aanya BhallaDivision of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas at Austin, Austin, Texas 78712, United States.
Eric CrowellDepartment of Ophthalmology, Dell Medical School, University of Texas at Austin, Austin, Texas 78701, United States.
Yan WangOffice of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland 20903, United States.
Bin QinOffice of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland 20903, United States.
Feng ZhangDivision of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0000-0002-5377-5841 Funding
Intramural FDA HHS FD999999
6 · The paper itselfAbstract
Drug delivery products based on poly(lactic-
Indexed as
DexamethasoneDrug ImplantsLactic AcidPolyglycolic AcidAnimalsDrug Delivery SystemsDrug LiberationIntravitreal InjectionsMalePolylactic Acid-Polyglycolic Acid CopolymerRabbitsDexamethasoneDrug ImplantsLactic AcidPolyglycolic AcidPolylactic Acid-Polyglycolic Acid Copolymerdexamethasoneintravitreal implantin vivo releaseOZURDEXpoly(lactic-co-glycolic acid) (PLGA)
Identifiers
PMID41160904
PMCPMC13531682
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