Evidence map›Paper›PMID 41160676›Full record

ArticleScience advances2025

A highly sensitive and multiplexed wireless sensing system with skin-like compliance and stretchability for wearable applications.

Zhilu Ye, Ganggang Zhao, Minye Yang, Yadong Xu, Yichong Ren, Zehua Chen, Syed Muntazir Andrabi, Jingwei Xie, Wei Gao, Zheng Yan and 1 more

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhilu YeDepartment of Electrical and Computer Engineering, University of Illinois Chicago, Chicago, IL 60607, USA.ORCID 0000-0002-0017-6722
Ganggang ZhaoDepartment of Mechanical & Aerospace Engineering, University of Missouri, Columbia, MO 65211, USA.ORCID 0000-0002-6363-5295
Minye YangDepartment of Electrical and Computer Engineering, University of Illinois Chicago, Chicago, IL 60607, USA.ORCID 0000-0002-4659-7063
Yadong XuDepartment of Chemical and Biomedical Engineering, University of Missouri, Columbia, MO 65211, USA.ORCID 0000-0001-8885-6433
Yichong RenDepartment of Electrical and Computer Engineering, University of Illinois Chicago, Chicago, IL 60607, USA.
Zehua ChenDepartment of Chemical and Biomedical Engineering, University of Missouri, Columbia, MO 65211, USA.ORCID 0009-0007-4138-584X
Syed Muntazir AndrabiDepartment of Surgery-Transplant and Mary and Dick Holland Regenerative Medicine Program, University of Nebraska Medical Center, Omaha, NE 68130, USA.ORCID 0000-0002-2998-2971
Jingwei XieDepartment of Surgery-Transplant and Mary and Dick Holland Regenerative Medicine Program, University of Nebraska Medical Center, Omaha, NE 68130, USA.ORCID 0000-0002-8126-1397
Wei GaoAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0002-8503-4562
Zheng YanDepartment of Mechanical & Aerospace Engineering, University of Missouri, Columbia, MO 65211, USA.ORCID 0000-0001-5968-0934
Pai-Yen ChenDepartment of Electrical and Computer Engineering, University of Illinois Chicago, Chicago, IL 60607, USA.ORCID 0000-0002-8112-8457

Funding

Multifunctional Porous Soft Materials for User-Friendly Skin-Interfaced Bimodal Cardiac Patches with Long-Term Biocompatibility and Antimicrobial PropertyR01EB033371 · NIBIB · UNIVERSITY OF MISSOURI-COLUMBIA · PI YAN, ZHENG · 2022 to 2025
$2.6M
Laser-Engraved Wearable Sweat Sensors to Detect and Monitor Cardiometabolic DiseaseR01HL155815 · NHLBI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI GAO, WEI · 2021 to 2025
$2.0M
NHLBI NIH HHS R01 HL155815NIBIB NIH HHS R01 EB033371
6 · The paper itself

Abstract

Wearable wireless sensing systems capable of monitoring critical biomarkers are increasingly valued for health monitoring and disease management. However, current systems often compromise on sensitivity, multi-parameter sensing capacity, compactness, power consumption, and wearing comfort, limiting their skin-interfaced applications. Here, we present a wireless, battery-free, multiplexed sensing system based on a high-order exceptional point (EP)-a singularity in non-Hermitian realm. This system features multiple distinct resonance frequencies that sensitively respond to physiological variations, exhibiting over 10-fold sensitivity improvement and 50% size reduction compared to conventional resonator-based systems. Moreover, the sensor employs a strain-resilient liquid metal composite and a soft substrate, ensuring wearing comfort, mechanical reliability, and antimicrobial properties. The effectiveness of this system is demonstrated through in situ monitoring of skin temperature and sweat electrolytes during exercise and prolonged monitoring of sweat glucose and ammonium in different subjects. The proposed system is highly transformative, offering benefits for various wearable applications.

Indexed as

Biosensing TechniquesSkinWearable Electronic DevicesWireless TechnologyEquipment DesignGlucoseHumansMonitoring, PhysiologicSkin TemperatureSweatGlucose

Identifiers

PMID41160676
PMCPMC12571053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.