ArticleScience advances2025
Pan-cortical cellular imaging in freely behaving mice using a miniaturized micro-camera array microscope (mini-MCAM).
Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- MIMAS: An open-source microlens-array miniature microscope for accessible large-field cortical imaging in freely behaving mice.Science advances · 2026Article
- Coordinated Representational Drift Across the Mouse Cortex.Research square · 2026Article
- CortexCAM: A Camera Array Microscope for Cortex-Wide Cellular Imaging in Freely Locomoting Mice.Research square · 2026Article
- Coordinated Representational Drift Across the Mouse Cortex.bioRxiv : the preprint server for biology · 2026Article
- Cortex-Wide Cellular Imaging in Freely Locomoting Mice Using Cortex Camera Array Microscope (CortexCAM).bioRxiv : the preprint server for biology · 2026Article
- Developmental maturation of millimeter-scale functional networks across brain areas.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Computer vision-guided open-source active commutator for neural imaging in freely behaving animals.Neurophotonics · 2024Article
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14 authors.
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Abstract
Understanding how circuits in the brain simultaneously coordinate their activity to mediate complex ethologically relevant behaviors requires recording neural activities from distributed populations of neurons in freely behaving animals. Current miniaturized imaging microscopes are typically limited to imaging a relatively small field of view (FOV), precluding the measurement of neural activities across multiple brain regions. Here, we present a miniaturized micro-camera array microscope (mini-MCAM) that consists of four fluorescence imaging micro-cameras, each capable of capturing neural activity across a 4.5 millimeter × 2.55 millimeter FOV. Cumulatively, the mini-MCAM images over a 30-square millimeter area of sparsely expressed GCaMP6s neurons that were distributed throughout the dorsal cortex, in regions including the primary and secondary motor, somatosensory, visual, retrosplenial, and association cortices across both hemispheres. We demonstrate cortex-wide cellular resolution in vivo calcium (Ca
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.