Evidence map›Paper›PMID 41160284›Full record

ArticleUpdates in surgery2026

Updates in surgery for colorectal cancer: incidence and risk factors for acute anastomotic leak-a retrospective study.

Tamer A A M Habeeb, Abdulzahra Hussain, Massimo Chiaretti, Igor A Kryvoruchko, Aristotelis Kechagias, Abd Al-Kareem Elias, Abdelmonem A M Adsam, Mohamed A Gadallah, Saad Mohamed Ali Ahmed, Ahmed Khyrallh and 34 more

Erratum issuedAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Updates in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

44 authors.

Tamer A A M HabeebDepartment of General Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt. tameralnaimy@hotmail.com.ORCID http://orcid.org/0000-0002-7049-4267
Abdulzahra HussainSheffield University, Sheffield, UK.
Massimo ChiarettiDepartment of General Surgery Specialties and Organ Transplant, Faculty of Pharmacy and Medicine, Sapienza Rome University, Rome, Italy.
Igor A KryvoruchkoDepartment of Surgery No. 2, Kharkiv National Medical University, Kharkiv, Ukraine.
Aristotelis KechagiasDepartment of Surgery, Athens Metropolitan General Hospital, University of Nicosia Medical School by HEAL Academy, Athens, Greece.
Abd Al-Kareem EliasDepartment of General Surgery, Faculty of Medicine, Al-Azhar University, Assuit Branch, Assuit, Egypt.
Abdelmonem A M AdsamDepartment of General Surgery, Faculty of Medicine, Al-Azhar University, Assuit Branch, Assuit, Egypt.
Mohamed A GadallahDepartment of General Surgery, Faculty of Medicine, Al-Azhar University, Assuit Branch, Assuit, Egypt.
Saad Mohamed Ali AhmedDepartment of General Surgery, Faculty of Medicine, Al-Azhar University, Assuit Branch, Assuit, Egypt.
Ahmed KhyrallhDepartment of General Surgery, Faculty of Medicine, Al-Azhar University, Assuit Branch, Assuit, Egypt.
Mohammed H AlsayedDepartment of General Surgery, Faculty of Medicine, Al-Azhar University, Assuit Branch, Assuit, Egypt.
Esmail Tharwat Kamel AwadDepartment of General Surgery, Faculty of Medicine, Al-Azhar University, Assuit Branch, Assuit, Egypt.
Emad A IbrahimDepartment of General Surgery, Faculty of Medicine, Al-Azhar University, Assuit Branch, Assuit, Egypt.
Mohamed Fathy LabibGeneral Surgery Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Sobhy Rezk Ahmed TeamaGeneral Surgery Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Mohamed Sobhy ShaabanGeneral Surgery Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Mohammed Hassan ElshafeyGeneral Surgery Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Abdelhafez SeleemGeneral Surgery Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Amr RadwanGeneral Surgery Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Hamada Rashad Mohamed AbdelkaderGeneral Surgery Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Ahmed Fayez OthmanDepartment of General Surgery, Faculty of Medicine for Girls, Al Azhar University, Cairo, Egypt.
Nasreldin Mohammed AlgalalyGeneral Surgery Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Mostafa Mahmoud Salama MostafaGeneral Surgery Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Mohammed Abbas Abdou AbouelseoudGeneral Surgery Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Mohamed Ibrahim Abo AlsaadGeneral Surgery-Faculty of Medicine, Merit University, Sohag, Egypt.
Abouelatta Kh AliMisr University for Science and Technology, Cairo, Egypt.
Hamdi ElbelkasiMataryia Teaching Hospital (GOTHI), Cairo, Egypt.
Mahmoud Ali Abou ZaidGeneral Surgery Department, El Mahala Hepatic Institute, Al Gharbia, Egypt.
Basma Ahmed MohamedDepartment of General Surgery, Faculty of Medicine for Girls, Al Azhar University, Cairo, Egypt.
Islam Mohamed IbrahimDepartment of General Surgery, Faculty of Medicine for Girls, Al Azhar University, Cairo, Egypt.
Ahmed Gamal Eldin MetwallyDepartment of General Surgery, Faculty of Medicine for Girls, Al Azhar University, Cairo, Egypt.
Mahmoud El AzawyDepartment of General Surgery, Helwan University, Cairo, Egypt.
Amr KhalilDepartment of Surgical Oncology, Al-Ahrar Teaching Hospital (GOTH), Zagazig, Egypt.
Sameh Tolba Abu-ElelaGeneral Surgery Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Ahmed Kamal El TaherDepartment of General Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Mahmoud Abdou YassinDepartment of General Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Mohamed LotfyDepartment of General Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Bassam MousaDepartment of General Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Baher AtefDepartment of General Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Mohamed ElnemrDepartment of General Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Ahmed Mesbah AbdelazizDepartment of General Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Tamer WasefyDepartment of General Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Mohamed Ibrahim MansourDepartment of General Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Abdelrahman Mohamed Hasanin NawarDepartment of General Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to analyze the incidence and risk factors of acute anastomotic leak (AL) in patients with colorectal cancer (CRC) during and after the COVID-19 pandemic. Active COVID-19 was evaluated as a risk factor of acute AL. A retrospective multicenter analysis was performed on 390 patients with CRC between April 2020 and October 2024. Patients were divided into acute AL (n = 27) and no acute AL (no AL) (n = 363) groups. In the acute AL group, there were 24 (88.8%) men and three (11.2%) women, with a median age of 63 (65-67) years. Twenty-seven patients in both groups had a previous COVID-19 infection and 15 patients (55.5%) who complained of COVID-19 had AL. The incidence of clinical AL was 6.9% (27/390), of which 11.1% (3/27) and 88.9% (24/27) were grade B and C, respectively. 24/27 (88.9%) had free AL with peritonitis requiring surgical re-intervention. Multivariate analysis showed that active COVID-19 infection (OR = 176, 95% CI 14.27-2172.57, p < 0.001) and serum albumin level < 3 g/dl (OR = 16.249, 95% CI 1.033-255.544, p = 0.04) were associated risk predictors of AL, while the laparoscopic approach (OR = 0.032, 95% CI 0.002-0.434, p = 0.01) and splenic flexure mobilization (OR = 0.022, 95% CI 0.003-4.844, p = 0.02) were protective. The incidence of AL after CRC surgery did not increase during or after the COVID-19 pandemic. Active COVID-19 and serum albumin levels < 3 g/dl were associated risk factors for AL, while the laparoscopic approach and splenic flexure mobilization were protective.

Indexed as

Anastomotic LeakColorectal NeoplasmsCOVID-19Acute DiseaseAgedFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesRisk FactorsAnastomotic leakColorectal cancerCOVID-19Risk factors

Identifiers

PMID41160284

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.