Evidence map›Paper›PMID 41160269›Full record

ArticleMedical oncology (Northwood, London, England)2025

Anticancer potential of chamaejasmenin B: apoptotic and antioxidant effects on pancreatic cancer cells.

Sedef Akçaalan, Canan Eroğlu Güneş, Leyla Asadova, Ercan Kurar

Abstract read
PubMed Publisher
In one paragraph

Article in Medical oncology (Northwood, London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sedef AkçaalanDepartment of Medical Biology, Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey. sakcaalan@erbakan.edu.tr.ORCID http://orcid.org/0000-0002-5559-3910
Canan Eroğlu GüneşDepartment of Medical Biology, Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.ORCID http://orcid.org/0000-0002-3796-575X
Leyla AsadovaDepartment of Medical Biology, Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.ORCID http://orcid.org/0000-0003-2736-187X
Ercan KurarDepartment of Medical Biology, Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.ORCID http://orcid.org/0000-0002-9234-1560

Funding

Necmettin Erbakan Üniversitesi # 221218024
6 · The paper itself

Abstract

The aim of this study was to investigate the effect of Chamaejasmenin B (CHB), a phytochemical, on human pancreatic cancer cell line (MIA PaCa-2). CCK-8 test was performed to evaluate the cytotoxic effect of CHB. To elucidate the molecular mechanism of CHB, expression levels of important genes in the cell cycle and apoptosis pathways were evaluated by qPCR and Western blot analysis. In addition, the effects of CHB on the colony formation capacity of cells, total oxidant and total antioxidant levels were also evaluated. The IC

Indexed as

Antineoplastic Agents, PhytogenicAntioxidantsApoptosisPancreatic NeoplasmsCell Line, TumorCell ProliferationHumansAntineoplastic Agents, PhytogenicAntioxidantsApoptosisCell cycleChamaejasmenin bPancreatic cancer

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.