Evidence map›Paper›PMID 41160112›Full record

ArticleNeuroradiology2025

Comparison of multiple tractography pipelines for corticospinal tract reconstruction applied to brain tumor patients.

Jianzhong He, Yifeng Cheng, Yiang Pan, Qingrun Zeng, Zhenqiu Xing, Qichuan Zhuge, Shun Yao, Yiheng Tan, Yuanjing Feng

Abstract readComparative Study
PubMed Publisher
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Article in Neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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9 authors.

Jianzhong HeZhejiang University of Technology, Hangzhou, China. hjzhong@zjut.edu.cn.
Yifeng ChengZhejiang University of Technology, Hangzhou, China.
Yiang PanZhejiang University of Technology, Hangzhou, China.
Qingrun ZengZhejiang University of Technology, Hangzhou, China.
Zhenqiu XingFirst Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Qichuan ZhugeFirst Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Shun YaoFirst Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yiheng TanFirst Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yuanjing FengZhejiang University of Technology, Hangzhou, China. fyjing@zjut.edu.cn.

Funding

Major science and technology special projects of Wenzhou ZS2017007National Natural Science Foundation of China 62303413National Natural Science Foundation of China U22A2040National Natural Science Foundation of China U23A20334Zhejiang Province Science and Technology Innovation Leading Talent Program 2021R52004
6 · The paper itself

Abstract

objectiveDetermining the best-performing corticospinal tract (CST) tractography pipelines based on the experts score for patients with four types of edema degree and tumor locations. MATERIALS AND

methodsTwenty-three patients were stratified into four groups based on tumor location and edema degree: tumors near the precentral cortex without edema, tumors near the precentral cortex with edema, tumors located deep without edema, and tumors located deep with edema. The dataset included 13 males and 10 females, with an average age of 51.04 ± 14.50 years. Diffusion MRI data (b = 1,000 s/mm

resultsTractSeg performed best for tumors without edema, achieving the highest expert score. UKF-2T and DSIstudio obtained the highest expert score when tumors with edema near the precentral cortex, and tumors located in deep brain, respectively. Quantitative results showed minimal interhemispheric differences in gray matter coverage for DSIstudio and UKF-2T, with slightly higher values on the healthy side. UKF-2T exhibited the highest CST volume. TractSeg generated the lowest false-positive streamlines.

conclusionsDifferent tumor locations and edema degrees require specific tractography pipelines. TractSeg is optimal for tumors without edema, while UKF-2T and DSIstudio are superior for tumors with edema.

Indexed as

Brain NeoplasmsDiffusion Tensor ImagingImage Interpretation, Computer-AssistedPyramidal TractsAdultBrain EdemaFemaleHumansMaleMiddle AgedCorticospinal tractDiffusion magnetic resonance imagingEdemaTractographyTumor

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