Evidence map›Paper›PMID 41159765›Full record

ArticleAmerican journal of respiratory and critical care medicine2026

Reply to Zhao and Li: Does upper airway volume truly predict adolescent brain structure and cognition?

Amal Isaiah

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Amal IsaiahDepartment of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, MD, United States.

Funding

Adolescent Brain Cognitive Development (ABCD) Prospective Research in Studies of Maturation (PRISM) ConsortiumU01DA041117 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE · PI LINDA CHANG, THOMAS M ERNST · 2015 to 2026
$19.5M
A mechanistic understanding of treatment-related outcomes of sleep disordered breathing using functional near infrared spectroscopyR01HL167012 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI Amal Isaiah · 2023 to 2026
$2.3M
NHLBI NIH HHS R01 HL167012NHLBI NIH HHS R01HL167012NIDA NIH HHS U01 DA041117
6 · The paper itself

Abstract

We appreciate the thoughtful critique by Zhao and Li of our recent study linking magnetic resonance imaging-derived upper airway volume to brain structure and cognition in adolescents.1 Their comments highlight considerations regarding craniofacial morphology, pubertal timing, scanner-related variability, and causal interpretation. We welcome the opportunity to clarify these issues.

Indexed as

BrainCognitionAdolescentFemaleHumansMagnetic Resonance ImagingMale

Identifiers

PMID41159765
PMCPMC12728952

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.