ReviewOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2025
Impact of contact lens correction on wavefront aberrations and vision quality in keratoconus.
Review in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Prospective pilot randomized controlled study of mini-scleral lenses versus rigid gas permeable lenses in irregular cornea with dry eye.Scientific reports · 2026Trial
- Reduced Image Quality Impairs Monocular Blur-Driven Accommodation in Keratoconus.Investigative ophthalmology & visual science · 2026Article
- Impact of a three-month period of mini-scleral lens usage on intraocular pressure and the anterior chamber angle in patients with keratoconus.International journal of ophthalmology · 2026Article
- Impact of contact lens correction on wavefront aberrations and vision quality in keratoconus.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo review the optical principles of contact lens correction in keratoconus, with a focus on residual ocular wavefront error and its impact on vision performance.
findingsCorneal rigid gas permeable (RGP) contact lenses, commonly used in keratoconus management, often fail to improve vision quality to levels observed in non-diseased eyes due to residual higher-order aberrations (HOAs), primarily originating from posterior corneal irregularity. Dependent on the nature of the residual wavefront error, various lens parameter modifications, including optic zone asphericity, base-down prism and scleral lens vault adjustments, can improve vision outcomes. Wavefront-guided corrections have demonstrated potential to provide vision quality equivalent to that of healthy eyes, particularly when sufficient time is allowed for neural adaptation. SUMMARY: This review examines the optical characteristics of the cornea in keratoconus, including the induction of elevated ocular wavefront errors. Challenges relating to optical correction with contact lenses are discussed, with an exploration of the origins of residual HOAs and their subsequent impacts on vision quality and quality-of-life. A range of contact lens modalities and parameter modifications are discussed, with evidence supporting their efficacy in reducing residual ocular wavefront error. Emerging data on wavefront-guided corrections are presented, along with future directions for personalised optical corrections tailored to individual patient presentations.
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Registered trials
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