Evidence map›Paper›PMID 41159326›Full record

ArticleHua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology2025

[Defect modification of calcium silicate and its application in oral bacteriostasis and tooth remineralization].

Yuanyuan Hu, Shuyan Zhang, Jianhua Zhang, Hongrong Luo, Yunfeng Li, Jing Zhang, Xianchun Chen

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
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Article in Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yuanyuan HuCollege of Polymer Science and Engineering, Sichuan University, Chengdu 610065, China.
Shuyan ZhangCollege of Polymer Science and Engineering, Sichuan University, Chengdu 610065, China.
Jianhua ZhangCollege of Polymer Science and Engineering, Sichuan University, Chengdu 610065, China.
Hongrong LuoNational Biomedical Materials Engineering Research Center, Sichuan University, Chengdu 610065, China.
Yunfeng LiState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Dept. of Orthognathic and Temporomandibular Joint Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Jing ZhangCollege of Architecture and Environment, Sichuan University, Chengdu 610065, China.
Xianchun ChenCollege of Polymer Science and Engineering, Sichuan University, Chengdu 610065, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCalcium silicate (CSO) is modified to give it photothermal antibacterial properties. Its application potential in tooth mineralization and oral antibacterial is evaluated.

methodsBased on defect-engineering modification strategy, a series of CSO-T samples (CSO-300, CSO-400, CSO-500, CSO-600) was obtained by introducing oxygen vacancy into CSO through thermal reduction using sodium borohydride. The samples were tested using scanning electron microscopy (SEM), X-ray diffraction, X-ray photoelectron spectroscopy, ultraviolet near-infrared absorption spectroscopy, and infrared thermography. The powder samples with the best photothermal performance and the most suitable material concentration (CSO-500, 500 μg/mL) were selected for subsequent experiments. High resolution transmission electron microscopy was used to analyze the microstructure and morphology of the sample, and MTT assay and Calcein AM/PI live/dead cell staining were used to evaluate the toxicity and compatibility of the sample to human oral keratinocytes.

resultsOxygen vacancies changed the crystal type and lattice spacing of CaSiO

conclusionsDefect-modified black calcium silicate has multiple functions, such as promoting tooth remineralization and photothermal bacteriostatic. When combined with the infrared luminescent toothbrush, it can simply and effectively treat tooth enamel erosion and oral bacteriostatic diseases caused by the excessive consumption of carbonated beverages and other daily bad living habits. This combination is expected to achieve the synergic treatment effect of tooth remineralization and oral bacteriostatic through daily cleaning is expected.

Indexed as

Anti-Bacterial AgentsCalcium CompoundsSilicatesTooth RemineralizationEscherichia coliHumansKeratinocytesMicroscopy, Electron, ScanningStaphylococcus aureusAnti-Bacterial AgentsCalcium Compoundscalcium silicateSilicatesbacteriostasiscalcium silicateoxygen vacancyphotothermal effecttooth remineralization

Identifiers

PMID41159326
PMCPMC12573702

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.