Evidence map›Paper›PMID 41159322›Full record

ArticleHua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology2025

[Expert consensus on clinical randomized controlled trial design and evaluation methods for bone grafting or substitute materials in alveolar bone defects].

Xiaoyu Liao, Yang Xue, Xueni Zheng, Enbo Wang, Jian Pan, Duohong Zou, Jihong Zhao, Bing Han, Changkui Liu, Hong Hua and 10 more

Abstract readEnglish AbstractConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Xiaoyu LiaoSchool of Stomatology, Xi'an Medical University; The Third Affiliated Hospital of Xi'an Medical University, Xi'an 710021, China.
Yang XueState Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Clinical Research Center for Oral Diseases, Dept. of Oral and Maxillofacial Surgery, The Third Affiliated Hospital of Air Force Medical University, Xi'an 710032, China.
Xueni ZhengState Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Clinical Research Center for Oral Diseases, Dept. of Oral and Maxillofacial Surgery, The Third Affiliated Hospital of Air Force Medical University, Xi'an 710032, China.
Enbo WangDept. of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.
Jian PanState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Duohong ZouShanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.
Jihong ZhaoDept. of Oral and Maxillofacial Surgery, Hospital of Stomatology, Wuhan University, Wuhan 430079, China.
Bing HanDept. of Oral and Maxillofacial Surgery, Hospital of Stomatology, Jilin University, Changchun 130021, China.
Changkui LiuSchool of Stomatology, Xi'an Medical University; The Third Affiliated Hospital of Xi'an Medical University, Xi'an 710021, China.
Hong HuaDept. of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.
Xinhua LiangState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Shuhuan ShangDept. of Oral and Maxillofacial Surgery, Hospital of Stomatology, Wuhan University, Wuhan 430079, China.
Wenmei WangStomatological Hospital Affiliated to Nanjing University Medical School, Nanjing 210093, China.
Shuibing LiuDept. of Pharmacology, School of Pharmacy, Air Force Medical University, Xi'an 710032, China.
Hu WangState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Pei WangState Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Clinical Research Center for Oral Diseases, Dept. of Oral and Maxillofacial Surgery, The Third Affiliated Hospital of Air Force Medical University, Xi'an 710032, China.
Bin FengState Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Clinical Research Center for Oral Diseases, Dept. of Oral and Maxillofacial Surgery, The Third Affiliated Hospital of Air Force Medical University, Xi'an 710032, China.
Jia JuState Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Clinical Research Center for Oral Diseases, Dept. of Oral and Maxillofacial Surgery, The Third Affiliated Hospital of Air Force Medical University, Xi'an 710032, China.
Linlin ZhangXi'an Deya Zhengshang Dental Clinic, Xi'an 710021, China.
Kaijin HuSchool of Stomatology, Xi'an Medical University; The Third Affiliated Hospital of Xi'an Medical University, Xi'an 710021, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone grafting is a primary method for treating bone defects. Among various graft materials, xenogeneic bone substitutes are widely used in clinical practice due to their abundant sources, convenient processing and storage, and avoidance of secondary surgeries. With the advancement of domestic production and the limitations of imported products, an increasing number of bone filling or grafting substitute materials isentering clinical trials. Relevant experts have drafted this consensus to enhance the management of medical device clinical trials, protect the rights of participants, and ensure the scientific and effective execution of trials. It summarizes clinical experience in aspects, such as design principles, participant inclusion/exclusion criteria, observation periods, efficacy evaluation metrics, safety assessment indicators, and quality control, to provide guidance for professionals in the field.

Indexed as

Bone SubstitutesBone TransplantationRandomized Controlled Trials as TopicConsensusHumansResearch DesignBone Substitutesalveolar bone defectalveolar bone defect measurementbone graft biomaterialsclinical trialridge preservation

Identifiers

PMID41159322
PMCPMC12573709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.