Evidence map›Paper›PMID 41159228›Full record

ReviewRevista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia2025

Current diagnostic approach to fungal infection in the critically ill patient.

Alfredo Maldonado-Barrueco, Inmaculada Quiles-Melero, Julio García-Rodríguez

Abstract readReview
In one paragraph

Review in Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alfredo Maldonado-BarruecoClinical Microbiology and Parasitology Department. Hospital Universitario La Paz. Madrid, Spain.ORCID 0000-0002-1856-1725
Inmaculada Quiles-MeleroClinical Microbiology and Parasitology Department. Hospital Universitario La Paz. Madrid, Spain.ORCID 0000-0001-5268-2902
Julio García-RodríguezClinical Microbiology and Parasitology Department. Hospital Universitario La Paz. Madrid, Spain. jgarciarodriguez@salud.madrid.org.ORCID 0000-0002-3771-8740

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive fungal infections are a major cause of morbidity and mortality in critically ill patients, with an increasing global incidence and species diversity, especially after the SARS-CoV-2 pandemic. Diagnosis relies on a combination of classical methods (microscopy, culture) and non-classical tools including biomarkers (1,3-β-D-glucan, galactomannan, mannan) and molecular assays. Fungal infections (candidiasis, aspergillosis, pneumocystosis, and mucormycosis) requires tailored diagnostic strategies based on host risk factors, epidemiology and specimen type. Combining diagnostic tests improves sensitivity and negative predictive value, guiding timely antifungal treatment. An integrated, pathogen-specific approach is essential to improve outcomes in the critical ill patient.

Indexed as

Invasive Fungal InfectionsMycosesAntifungal AgentsBiomarkersCOVID-19Critical IllnessGalactoseHumansMannansSARS-CoV-2Antifungal AgentsBiomarkersgalactomannanGalactoseMannansAspergillusCandidaMucoralesPneumocystis jirovecii

Identifiers

PMID41159228
PMCPMC12584900

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.