Evidence map›Paper›PMID 41159227›Full record

ReviewRevista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia2025

Syndromic platforms in the management of infection in the critically ill patient: test indication and diagnostic interpretation.

Sara Sanz, Natalia Burillo, Juan Manuel García-Lechuz

Abstract readReview
In one paragraph

Review in Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sara SanzServicio de Microbiología, Hospital Miguel Servet, Zaragoza, España.ORCID 0009-0000-8033-1720
Natalia BurilloServicio de Microbiología, Hospital Miguel Servet, Zaragoza, España.ORCID 0009-0002-1982-1469
Juan Manuel García-LechuzServicio de Microbiología, Hospital Miguel Servet, Zaragoza, España. jmgarcialechuz@salud.aragon.es.ORCID 0000-0002-9582-5472

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The timely and appropriate administration of empirical antibiotic therapy is critical for patient survival. However, several studies suggest that approximately 20-30% of patients presenting with sepsis receive inadequate antibiotic treatment, a factor strongly associated with increased mortality. Furthermore, approximately 20% of these patients experience adverse effects. The emergence of multidrug-resistant bacteria has significantly complicated the selection of appropriate antibiotic therapy and contributed to increased mortality. This challenge is particularly pronounced in conditions such as ventilator-associated pneumonia and bacteremia of various origins, which represent some of the most common infectious pathologies in the intensive care unit. This has resulted in the development of a range of rapid diagnostic tools, including syndromic panels. The primary objective of these panels is to identify the causative agent of infection at an early stage and to guide the selection of the optimal treatment as quickly as possible.

Indexed as

Anti-Bacterial AgentsCritical IllnessBacteremiaHumansIntensive Care UnitsPneumonia, Ventilator-AssociatedSepsisAnti-Bacterial AgentsCritically ill patientMultidrug-resistant pathogensSyndromic molecular diagnosis

Identifiers

PMID41159227
PMCPMC12584904

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.