ArticleRSC advances2025
Citric acid cross-linked honey and aloe vera gel loaded chitosan hydrogels for wound dressing applications.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Recent advances in chitosan-based nanomaterials for enhanced antimicrobial activity.World journal of microbiology & biotechnology · 2026Review
- Plasticization of an Ageratum Conyzoides Natural Extract in Crosslinked Hydrogel: a Promising Material for Combating Wound Infection.Applied biochemistry and biotechnology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic wounds pose a global challenge, often requiring the use of multifunctional materials that facilitate healing while protecting against infection. The present study develops porous, biodegradable and antibacterial composite hydrogels from chitosan and polyvinyl alcohol (PVA) incorporating honey and aloe vera gel as antimicrobial agents for healing chronic wounds. Hydrogels were prepared by freeze gelation methodology, and further crosslinked with citric acid. FTIR spectra confirmed the presence of characteristic functional groups and showed a reduction in the peak intensities of O-H, N-H, and amide bands in crosslinked hydrogels. Scanning electron micrographs illustrated the clear morphological changes; citric acid crosslinked hydrogels (GG-05, GG-06, GG-08) exhibited more porous, sponge-like structures, with GG-08 achieving the highest porosity, having an average pore size of 21.28 μm. The hydrogel GG-08 demonstrated the greatest water retention capacity, reaching up to 218%, while GG-04 showed the highest degradation of 93% ± 3. The developed hydrogels exhibited better antibacterial properties, especially GG-03, GG-04, GG-07 and GG-08 had excellent activity against Gram-positive
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.